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Identifying qualitative differences in PPARα signaling networks in human and rat hepatocytes and their significance for next generation chemical risk assessment methods.
McMullen, Patrick D; Bhattacharya, Sudin; Woods, Courtney G; Pendse, Salil N; McBride, Mary T; Soldatow, Valerie Y; Deisenroth, Chad; LeCluyse, Edward L; Clewell, Rebecca A; Andersen, Melvin E.
Afiliação
  • McMullen PD; ScitoVation LLC, 100 Capitola Drive, Suite 106, Durham, NC 277139, United States of America.
  • Bhattacharya S; Department of Biomedical Engineering and Department of Pharmacology & Toxicology, Michigan State University, East Lansing, MI 48824, United States of America.
  • Woods CG; School of Public Health, University of NC, Chapel Hill, NC 27599, United States of America.
  • Pendse SN; ScitoVation LLC, 100 Capitola Drive, Suite 106, Durham, NC 277139, United States of America.
  • McBride MT; Agilent Technologies, 7145 Via Solana, San Jose, CA 93135, United States of America.
  • Soldatow VY; LifeNet Health, Six Davis Drive, Research Triangle Park, NC 27709, United States of America.
  • Deisenroth C; ScitoVation LLC, 100 Capitola Drive, Suite 106, Durham, NC 277139, United States of America.
  • LeCluyse EL; LifeNet Health, Six Davis Drive, Research Triangle Park, NC 27709, United States of America.
  • Clewell RA; 21st Century Tox Consulting, Chapel Hill, NC 27516, United States of America.
  • Andersen ME; ScitoVation LLC, 100 Capitola Drive, Suite 106, Durham, NC 277139, United States of America. Electronic address: mandersen@scitovation.com.
Toxicol In Vitro ; 64: 104463, 2020 Apr.
Article em En | MEDLINE | ID: mdl-31628012
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Medição de Risco / Hepatócitos / PPAR alfa Tipo de estudo: Etiology_studies / Qualitative_research / Risk_factors_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Medição de Risco / Hepatócitos / PPAR alfa Tipo de estudo: Etiology_studies / Qualitative_research / Risk_factors_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article