Ensemble structural analyses depict the regulatory mechanism of non-phosphorylated human MAP2K4.

Matsumoto, Takashi; Yamano, Akihito; Murakawa, Yuka; Fukada, Harumi; Sawa, Masaaki; Kinoshita, Takayoshi

Matsumoto, Takashi; Yamano, Akihito; Murakawa, Yuka; Fukada, Harumi; Sawa, Masaaki; Kinoshita, Takayoshi.

Afiliação

Matsumoto T; Rigaku Corporation, 3-9-12 Matsubara-cho, Akishima, Tokyo, 196-8666, Japan. Electronic address: t-matumo@rigaku.co.jp.
Yamano A; Rigaku Corporation, 3-9-12 Matsubara-cho, Akishima, Tokyo, 196-8666, Japan.
Murakawa Y; Graduate School of Science, Osaka Prefecture University, 1-1 Gakuencho, Sakai, Osaka, 599-8531, Japan.
Fukada H; Graduate School of Science, Osaka Prefecture University, 1-1 Gakuencho, Sakai, Osaka, 599-8531, Japan.
Sawa M; Carna Biosciences, Inc., Hyogo, 650-0047, Japan.
Kinoshita T; Graduate School of Science, Osaka Prefecture University, 1-1 Gakuencho, Sakai, Osaka, 599-8531, Japan.

Biochem Biophys Res Commun ; 521(1): 106-112, 2020 01 01.

Article em En | MEDLINE | ID: mdl-31635803

Assuntos

MAP Quinase Quinase 4/análise; MAP Quinase Quinase 4/metabolismo; Trifosfato de Adenosina/química; Trifosfato de Adenosina/metabolismo; Humanos; Conformação Proteica; Espalhamento a Baixo Ângulo; Difração de Raios X

Palavras-chave

Ensemble optimization method; MAP2K4; Molecular fluctuation; Regulatory mechanism; Small angle X-ray scattering

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: MAP Quinase Quinase 4 Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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