[The brain imaging studies of obstructive sleep apnea: evidence from resting-state EEG and fMRI].
Sheng Li Xue Bao
; 71(5): 760-768, 2019 Oct 25.
Article
em Zh
| MEDLINE
| ID: mdl-31646330
ABSTRACT
Obstructive sleep apnea (OSA) is a common clinic sleep disorder, and characterized by obstruction of upper airway during sleep, resulting in sleep fragmentation and intermittent hypoxemia. We reviewed the brain imaging studies in OSA patients compared with healthy subjects, including studies of functional magnetic resonance imaging (fMRI) and electroencephalography (EEG). The resting-state EEG studies showed increased power of δ and θ in the front and central regions of the cerebral cortex in OSA patients. While resting-state fMRI studies demonstrated altered large-scale networks in default-mode network (DMN), central executive network (CEN) and salience network (SN). Evidence from resting-state studies of both fMRI and EEG focused on the abnormal activity in prefrontal cortex (PFC), which is correlated with OSA severity. These findings suggested that the PFC may play a key role in the abnormal function of OSA patients. Finally, based on the perspectives of treatment effect, multimodal data acquisition, and comorbidities, we discussed the future research direction of the neuroimaging study of OSA.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Encéfalo
/
Mapeamento Encefálico
/
Apneia Obstrutiva do Sono
Limite:
Humans
Idioma:
Zh
Ano de publicação:
2019
Tipo de documento:
Article