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First-in-human clinical trial to assess pharmacokinetics, pharmacodynamics, safety, and tolerability of iscalimab, an anti-CD40 monoclonal antibody.
Espié, Pascal; He, YanLing; Koo, Phillip; Sickert, Denise; Dupuy, Cyrielle; Chokoté, Edwige; Schuler, Roland; Mergentaler, Heidi; Ristov, Jacinda; Milojevic, Julie; Verles, Aurelie; Groenewegen, Andrea; Auger, Anita; Avrameas, Alexandre; Rotte, Michael; Colin, Laurence; Tomek, Charles S; Hernandez-Illas, Martha; Rush, James S; Gergely, Peter.
Afiliação
  • Espié P; Novartis Institutes for BioMedical Research, Basel, Switzerland.
  • He Y; Novartis Institutes for BioMedical Research, Inc., Cambridge, Massachusetts, USA.
  • Koo P; Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA.
  • Sickert D; Novartis Institutes for BioMedical Research, Basel, Switzerland.
  • Dupuy C; Novartis Institutes for BioMedical Research, Basel, Switzerland.
  • Chokoté E; Novartis Institutes for BioMedical Research, Basel, Switzerland.
  • Schuler R; Novartis Institutes for BioMedical Research, Basel, Switzerland.
  • Mergentaler H; Novartis Institutes for BioMedical Research, Basel, Switzerland.
  • Ristov J; Novartis Institutes for BioMedical Research, Basel, Switzerland.
  • Milojevic J; Novartis Institutes for BioMedical Research, Basel, Switzerland.
  • Verles A; Novartis Institutes for BioMedical Research, Basel, Switzerland.
  • Groenewegen A; Novartis Institutes for BioMedical Research, Basel, Switzerland.
  • Auger A; Novartis Institutes for BioMedical Research, Basel, Switzerland.
  • Avrameas A; Novartis Institutes for BioMedical Research, Basel, Switzerland.
  • Rotte M; Novartis Institutes for BioMedical Research, Basel, Switzerland.
  • Colin L; Novartis Institutes for BioMedical Research, Inc., Cambridge, Massachusetts, USA.
  • Tomek CS; Celerion, Inc., Lincoln, Nebraska, USA.
  • Hernandez-Illas M; QPS Miami, South Miami, Florida, USA.
  • Rush JS; Novartis Institutes for BioMedical Research, Basel, Switzerland.
  • Gergely P; Novartis Institutes for BioMedical Research, Basel, Switzerland.
Am J Transplant ; 20(2): 463-473, 2020 02.
Article em En | MEDLINE | ID: mdl-31647605
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Imunossupressores / Anticorpos Monoclonais Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies Limite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Imunossupressores / Anticorpos Monoclonais Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies Limite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article