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DNA epigenetic signature predictive of benefit from neoadjuvant chemotherapy in oesophageal adenocarcinoma: results from the MRC OE02 trial.
Sundar, Raghav; Ng, Alvin; Zouridis, Hermioni; Padmanabhan, Nisha; Sheng, Taotao; Zhang, Shenli; Lee, Ming Hui; Ooi, Wen Fong; Qamra, Aditi; Inam, Imran; Hewitt, Lindsay C; So, Jimmy Bok-Yan; Koh, Vivien; Nankivell, Matthew G; Langley, Ruth E; Allum, William H; Cunningham, David; Rozen, Steven G; Yong, Wei Peng; Grabsch, Heike I; Tan, Patrick.
Afiliação
  • Sundar R; Department of Haematology-Oncology, National University Health System, Singapore; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore; Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
  • Ng A; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore; Centre for Computational Biology, Duke-NUS Medical School, Singapore; NUS Graduate School for Integrative Sciences and Engineering, Singapore.
  • Zouridis H; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore; Technology Innovation and Delivery Excellence, AstraZeneca, USA.
  • Padmanabhan N; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.
  • Sheng T; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.
  • Zhang S; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.
  • Lee MH; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.
  • Ooi WF; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.
  • Qamra A; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.
  • Inam I; Division of Pathology and Data Analytics, Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK.
  • Hewitt LC; Department of Pathology, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Center+, Maastricht, the Netherlands.
  • So JB; Department of Surgery, National University Health System, Singapore; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
  • Koh V; Department of Haematology-Oncology, National University Health System, Singapore; Cancer Science Institute of Singapore, National University of Singapore, Singapore.
  • Nankivell MG; MRC Clinical Trials Unit at University College London, London, UK.
  • Langley RE; MRC Clinical Trials Unit at University College London, London, UK.
  • Allum WH; Department of Surgery, Royal Marsden Hospital, London, UK.
  • Cunningham D; Department of Medicine, The Royal Marsden NHS Trust, London and Sutton, United Kingdom.
  • Rozen SG; Centre for Computational Biology, Duke-NUS Medical School, Singapore.
  • Yong WP; Department of Haematology-Oncology, National University Health System, Singapore; Cancer Science Institute of Singapore, National University of Singapore, Singapore.
  • Grabsch HI; Division of Pathology and Data Analytics, Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK; Department of Pathology, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Center+, Maastricht, the Netherlands. Electronic address: h.grabsc
  • Tan P; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore; Cancer Science Institute of Singapore, National University of Singapore, Singapore; Biomedical Research Council, Agency for Science, Technology and Research, Singapore; SingHealth/Duke-NUS Institute of Precision Medicine, Nati
Eur J Cancer ; 123: 48-57, 2019 12.
Article em En | MEDLINE | ID: mdl-31655359
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Esofágicas / Adenocarcinoma / Protocolos de Quimioterapia Combinada Antineoplásica / Metilação de DNA / Terapia Neoadjuvante / Epigênese Genética Tipo de estudo: Clinical_trials / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Esofágicas / Adenocarcinoma / Protocolos de Quimioterapia Combinada Antineoplásica / Metilação de DNA / Terapia Neoadjuvante / Epigênese Genética Tipo de estudo: Clinical_trials / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article