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[Antihemagglutinin exhaustion reaction in studying the activity of arbovirus antigenic preparations]. / Reaktsiia istoshcheniia antigemaggliutininov v izuchenii aktivnosti antigennykh preparatov arbovirusov.
Vopr Virusol ; (6): 646-51, 1979.
Article em Ru | MEDLINE | ID: mdl-316617
ABSTRACT
A modification of serological tests, the antihemagglutinin exhaustion test, was developed for the study of capacity of different fractions of the antigenic preparations of tick-borne encephalitis and western equine encephalomyelitis viruses to react with antibody. The test is simple to perform, highly sensitive and specific which permits within a very short time to examine the antigenic activity of practically all, including non-hemagglutinating, virus fractions obtained by gel chromatography and ultracentrifugation. Significant functional heterogeneity of virus particles in interaction with antibody was established. Non-hemagglutinating virions were capable of binding antihemagglutinins. The intensity of interaction with antibody of the most active virus fractions in the HI and CF tests was considerably higher than that of nonfractionated preparations.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Arbovírus / Testes de Inibição da Hemaglutinação / Anticorpos Anti-Idiotípicos / Hemaglutininas Virais / Antígenos Virais Limite: Animals Idioma: Ru Ano de publicação: 1979 Tipo de documento: Article
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Arbovírus / Testes de Inibição da Hemaglutinação / Anticorpos Anti-Idiotípicos / Hemaglutininas Virais / Antígenos Virais Limite: Animals Idioma: Ru Ano de publicação: 1979 Tipo de documento: Article