The release of tryptase from mast cells promote tumor cell metastasis via exosomes.

Xiao, Hui; He, Mudan; Xie, Guogang; Liu, Yanan; Zhao, Yuxia; Ye, Xiong; Li, Xingjing; Zhang, Min

Xiao, Hui; He, Mudan; Xie, Guogang; Liu, Yanan; Zhao, Yuxia; Ye, Xiong; Li, Xingjing; Zhang, Min.

Afiliação

Xiao H; Department of Respiratory and Critical Care Medicine, Shanghai General Hospital, Shanghai Jiaotong University, 85 Wujin Road, Shanghai, 200080, China.
He M; Department of Respiratory and Critical Care Medicine, Shanghai General Hospital of Baoshan Branch, Shanghai, China.
Xie G; Department of Respiratory and Critical Care Medicine, Shanghai General Hospital, Shanghai Jiaotong University, 85 Wujin Road, Shanghai, 200080, China.
Liu Y; Department of Clinical Laboratory, Shanghai Children's Hospital, Shanghai Jiaotong University, Shanghai, China.
Zhao Y; College of Clinical Medicine, Shanghai University of Medicine & Health Science, Shanghai, China.
Ye X; College of Clinical Medicine, Shanghai University of Medicine & Health Science, Shanghai, China. ye-xiong@163.com.
Li X; Department of Respiratory and Critical Care Medicine, Shanghai General Hospital of Baoshan Branch, Shanghai, China. xingjingli618@163.com.
Zhang M; Department of Respiratory and Critical Care Medicine, Shanghai General Hospital, Shanghai Jiaotong University, 85 Wujin Road, Shanghai, 200080, China. minzhang20190123@163.com.

BMC Cancer ; 19(1): 1015, 2019 Oct 29.

Article em En | MEDLINE | ID: mdl-31664930

Assuntos

Adenocarcinoma de Pulmão/metabolismo; Adenocarcinoma de Pulmão/secundário; Exossomos/metabolismo; Neoplasias Pulmonares/metabolismo; Neoplasias Pulmonares/secundário; Mastócitos/metabolismo; Triptases/metabolismo; Células A549; Adenocarcinoma de Pulmão/patologia; Células da Medula Óssea/metabolismo; Degranulação Celular; Movimento Celular; Proliferação de Células; Citocinas/metabolismo; Células Endoteliais da Veia Umbilical Humana; Humanos; Janus Quinases/metabolismo; Neoplasias Pulmonares/patologia; Fatores de Transcrição STAT/metabolismo; Transdução de Sinais; Fator de Células-Tronco/metabolismo

Palavras-chave

Angiogenesis; Exosomes; Lung cancer; Mast cell; Tryptase

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Triptases / Exossomos / Adenocarcinoma de Pulmão / Neoplasias Pulmonares / Mastócitos Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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