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GX15-070 (Obatoclax), a Bcl-2 family proteins inhibitor engenders apoptosis and pro-survival autophagy and increases Chemosensitivity in neuroblastoma.
Cournoyer, Sonia; Addioui, Anissa; Belounis, Assila; Beaunoyer, Mona; Nyalendo, Carine; Le Gall, Roxane; Teira, Pierre; Haddad, Elie; Vassal, Gilles; Sartelet, Hervé.
Afiliação
  • Cournoyer S; Research Center, Sainte Justine University Hospital Center, Montreal, QC, Canada.
  • Addioui A; Research Center, Sainte Justine University Hospital Center, Montreal, QC, Canada.
  • Belounis A; Department of Pathology and Cellular Biology, Université de Montréal, Montreal, QC, Canada.
  • Beaunoyer M; Research Center, Sainte Justine University Hospital Center, Montreal, QC, Canada.
  • Nyalendo C; Department of Pathology and Cellular Biology, Université de Montréal, Montreal, QC, Canada.
  • Le Gall R; Research Center, Sainte Justine University Hospital Center, Montreal, QC, Canada.
  • Teira P; Department of Pediatric Surgery, Sainte-Justine University Hospital Center, Montreal, QC, Canada.
  • Haddad E; Research Center, Sainte Justine University Hospital Center, Montreal, QC, Canada.
  • Vassal G; Research Center, Sainte Justine University Hospital Center, Montreal, QC, Canada.
  • Sartelet H; Research Center, Sainte Justine University Hospital Center, Montreal, QC, Canada.
BMC Cancer ; 19(1): 1018, 2019 Oct 29.
Article em En | MEDLINE | ID: mdl-31664947
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirróis / Autofagia / Apoptose / Neoplasias das Glândulas Suprarrenais / Resistencia a Medicamentos Antineoplásicos / Proteínas Proto-Oncogênicas c-bcl-2 / Neuroblastoma / Antineoplásicos Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirróis / Autofagia / Apoptose / Neoplasias das Glândulas Suprarrenais / Resistencia a Medicamentos Antineoplásicos / Proteínas Proto-Oncogênicas c-bcl-2 / Neuroblastoma / Antineoplásicos Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article