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Altered chromosomal topology drives oncogenic programs in SDH-deficient GISTs.
Flavahan, William A; Drier, Yotam; Johnstone, Sarah E; Hemming, Matthew L; Tarjan, Daniel R; Hegazi, Esmat; Shareef, Sarah J; Javed, Nauman M; Raut, Chandrajit P; Eschle, Benjamin K; Gokhale, Prafulla C; Hornick, Jason L; Sicinska, Ewa T; Demetri, George D; Bernstein, Bradley E.
Afiliação
  • Flavahan WA; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Drier Y; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Johnstone SE; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. yotam.drier@mail.huji.ac.il.
  • Hemming ML; Broad Institute of MIT and Harvard, Cambridge, MA, USA. yotam.drier@mail.huji.ac.il.
  • Tarjan DR; The Lautenberg Center for Immunology and Cancer Research, IMRIC, Faculty of Medicine, The Hebrew University, Jerusalem, Israel. yotam.drier@mail.huji.ac.il.
  • Hegazi E; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Shareef SJ; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Javed NM; Center for Sarcoma and Bone Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Raut CP; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School Boston, Boston, MA, USA.
  • Eschle BK; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Gokhale PC; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Hornick JL; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Sicinska ET; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Demetri GD; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Bernstein BE; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Nature ; 575(7781): 229-233, 2019 11.
Article em En | MEDLINE | ID: mdl-31666694
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oncogenes / Succinato Desidrogenase / Aberrações Cromossômicas / Tumores do Estroma Gastrointestinal / Carcinogênese Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oncogenes / Succinato Desidrogenase / Aberrações Cromossômicas / Tumores do Estroma Gastrointestinal / Carcinogênese Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article