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Identification of Absidia orchidis steroid 11ß-hydroxylation system and its application in engineering Saccharomyces cerevisiae for one-step biotransformation to produce hydrocortisone.
Chen, Jing; Fan, Feiyu; Qu, Ge; Tang, Jinlei; Xi, Yongyan; Bi, Changhao; Sun, Zhoutong; Zhang, Xueli.
Afiliação
  • Chen J; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, China; Key Laboratory of Systems Microbial Biotechnology, Chinese Academy of Sciences, China; University of Chinese Academy of Sciences, China.
  • Fan F; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, China; Key Laboratory of Systems Microbial Biotechnology, Chinese Academy of Sciences, China.
  • Qu G; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, China.
  • Tang J; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, China; Key Laboratory of Systems Microbial Biotechnology, Chinese Academy of Sciences, China.
  • Xi Y; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, China; Key Laboratory of Systems Microbial Biotechnology, Chinese Academy of Sciences, China; University of Chinese Academy of Sciences, China.
  • Bi C; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, China; Key Laboratory of Systems Microbial Biotechnology, Chinese Academy of Sciences, China.
  • Sun Z; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, China.
  • Zhang X; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, China; Key Laboratory of Systems Microbial Biotechnology, Chinese Academy of Sciences, China. Electronic address: zhang_xl@tib.cas.cn.
Metab Eng ; 57: 31-42, 2020 01.
Article em En | MEDLINE | ID: mdl-31669370
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Saccharomyces cerevisiae / Proteínas Fúngicas / Hidrocortisona / Absidia / Sistema Enzimático do Citocromo P-450 / Engenharia Metabólica Tipo de estudo: Diagnostic_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Saccharomyces cerevisiae / Proteínas Fúngicas / Hidrocortisona / Absidia / Sistema Enzimático do Citocromo P-450 / Engenharia Metabólica Tipo de estudo: Diagnostic_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Article