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DL0410 ameliorates cognitive deficits in APP/PS1 transgenic mice by promoting synaptic transmission and reducing neuronal loss.
Zhou, Wei; Lian, Wen-Wen; Yan, Rong; Jia, Hao; Xu, Lv-Jie; Wang, Lin; Liu, Ai-Lin; Du, Guan-Hua.
Afiliação
  • Zhou W; Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
  • Lian WW; Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
  • Yan R; Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
  • Jia H; Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
  • Xu LJ; Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
  • Wang L; Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
  • Liu AL; Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China. liuailin@imm.ac.cn.
  • Du GH; Beijing Key Laboratory of Drug Target Research and Drug Screening, Beijing, 100050, China. liuailin@imm.ac.cn.
Acta Pharmacol Sin ; 41(5): 599-611, 2020 May.
Article em En | MEDLINE | ID: mdl-31685977
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piperidinas / Compostos de Bifenilo / Transmissão Sináptica / Fármacos Neuroprotetores / Disfunção Cognitiva / Neurônios Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piperidinas / Compostos de Bifenilo / Transmissão Sináptica / Fármacos Neuroprotetores / Disfunção Cognitiva / Neurônios Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article