Development of a method for identifying and functionally analyzing allele-specific DNA methylation based on BS-seq data.

Zhu, Jiang; Su, Mu; Gu, Yue; Zhang, Xingda; Lv, Wenhua; Zhang, Shumei; Sun, Zhongyi; Lu, Haibo; Zhang, Yan

Zhu, Jiang; Su, Mu; Gu, Yue; Zhang, Xingda; Lv, Wenhua; Zhang, Shumei; Sun, Zhongyi; Lu, Haibo; Zhang, Yan.

Afiliação

Zhu J; School of Life Science & Technology, Computational Biology Research Center, Harbin Institute of Technology, Harbin 150001, PR China.
Su M; Medical Laboratory Technology College, Daqing Branch of Harbin Medical University, Daqing, Heilongjiang, 163319, PR China.
Gu Y; State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou, 51000, PR China.
Zhang X; College of Bioinformatics Science & Technology, Harbin Medical University, Harbin, Heilongjiang, 150081, PR China.
Lv W; State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou, 51000, PR China.
Zhang S; State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou, 51000, PR China.
Sun Z; Medical Laboratory Technology College, Daqing Branch of Harbin Medical University, Daqing, Heilongjiang, 163319, PR China.
Lu H; Department of Breast Surgery, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, 150081, PR China.
Zhang Y; Medical Laboratory Technology College, Daqing Branch of Harbin Medical University, Daqing, Heilongjiang, 163319, PR China.

Epigenomics ; 11(15): 1679-1692, 2019 11 01.

Article em En | MEDLINE | ID: mdl-31701777

Assuntos

Metilação de DNA/genética; Genoma Humano/genética; Alelos; Epigênese Genética/genética; Impressão Genômica/genética; Haplótipos/genética; Sequenciamento de Nucleotídeos em Larga Escala/métodos; Humanos; Linfócitos/fisiologia; Polimorfismo de Nucleotídeo Único/genética; Análise de Sequência de DNA/métodos; Sequenciamento Completo do Genoma/métodos

Palavras-chave

allele-specific DNA methylation; genomic imprinting; high-throughput sequencing; single-nucleotide polymorphism

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Genoma Humano / Metilação de DNA Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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