Treatment of a stage III rima glottidis patient with the oncolytic virus Rigvir: A retrospective case report.
Medicine (Baltimore)
; 98(45): e17883, 2019 Nov.
Article
em En
| MEDLINE
| ID: mdl-31702662
ABSTRACT
RATIONALE Of all the parts of the larynx, the glottis has the highest frequency of cancer. With disease progression, the vocal cord movement is affected and for advanced stages its anatomical and functional preservation is rarely achievable, if at all. PATIENT CONCERNS Here we describe a 72-year-old patient who presented with hoarseness for a year and was only able to whisper. DIAGNOSIS A computed tomography (CT) scan of the vocal cords (without contrast) showed higher density tissue. Histological examination disclosed a well-differentiated verrucous squamous cell carcinoma of the glottis. INTERVENTIONS:
The patient was treated with the oncolytic ECHO-7 virus Rigvir without any of the standard treatments.OUTCOMES:
As shown by CT scans, the patient has been stabilized, and the laryngeal functions are preserved with the virotherapy still ongoing. The patient was diagnosed over 4.2 years ago. LESSONS Considering the present patient being treated with Rigvir without any standard treatment, the results suggest that Rigvir therapy could be a possible treatment for glottic cancer.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Laríngeas
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Terapia Viral Oncolítica
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Carcinoma de Células Escamosas de Cabeça e Pescoço
Limite:
Aged
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Humans
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Male
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article