Is lactic acidosis predictive of outcomes in pediatric diabetic ketoacidosis?
Am J Emerg Med
; 38(2): 329-332, 2020 02.
Article
em En
| MEDLINE
| ID: mdl-31704063
ABSTRACT
OBJECTIVES:
The objective of this study was to investigate the significance and prevalence of lactic acidosis in pediatric diabetic ketoacidosis (DKA) presenting to the emergency department.METHODS:
A retrospective cohort study of children (ageâ¯≤â¯21â¯years) presenting to a tertiary care emergency department in DKA from December 1, 2015 to December 1, 2018. Patients needed to have DKA requiring admission to the pediatric intensive care unit and have had a lactate level collected while in the emergency department to be included.RESULTS:
92 patients resulting in 113 encounters had DKA and a lactate level collected in the emergency department. The mean lactate level was 3.5â¯mmol/L (±SD 2.1). 72 (63.7%) encounters had lactic acidosis (pâ¯<â¯0.001). There was no significant association between the presence of lactic acidosis and pediatric intensive care unit length of stay (pâ¯=â¯0.321), hospital length of stay (pâ¯=â¯0.426), morbidity (pâ¯=â¯0.552) and mortality (pâ¯=â¯1.000). Initial glucose levels were significantly higher in the patients presenting with lactic acidosis (pâ¯=â¯0.001).CONCLUSIONS:
Lactic acidosis is a common finding in pediatric DKA patients presenting to the emergency department. Serum lactate alone should not be used as an outcome predictor in pediatric DKA.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Acidose Láctica
/
Mortalidade Hospitalar
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Cetoacidose Diabética
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Tempo de Internação
Tipo de estudo:
Observational_studies
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Prevalence_studies
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Prognostic_studies
/
Risk_factors_studies
Limite:
Adolescent
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Child
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Female
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Humans
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Male
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article