The Identification of Potential Therapeutic Targets for Cutaneous Squamous Cell Carcinoma.

McHugh, Angela; Fernandes, Kenneth; Chinner, Nerime; Ibrahim, Adel F M; Garg, Amit K; Boag, Garry; Hepburn, Lydia A; Proby, Charlotte M; Leigh, Irene M; Saville, Mark K

The Identification of Potential Therapeutic Targets for Cutaneous Squamous Cell Carcinoma.

McHugh, Angela; Fernandes, Kenneth; Chinner, Nerime; Ibrahim, Adel F M; Garg, Amit K; Boag, Garry; Hepburn, Lydia A; Proby, Charlotte M; Leigh, Irene M; Saville, Mark K.

Afiliação

McHugh A; Division of Cancer Research, School of Medicine, University of Dundee, Dundee, United Kingdom.
Fernandes K; Division of Cancer Research, School of Medicine, University of Dundee, Dundee, United Kingdom.
Chinner N; Division of Cancer Research, School of Medicine, University of Dundee, Dundee, United Kingdom.
Ibrahim AFM; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, United Kingdom.
Garg AK; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, United Kingdom.
Boag G; Division of Cancer Research, School of Medicine, University of Dundee, Dundee, United Kingdom.
Hepburn LA; Division of Cancer Research, School of Medicine, University of Dundee, Dundee, United Kingdom.
Proby CM; Division of Cancer Research, School of Medicine, University of Dundee, Dundee, United Kingdom; Division of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee, United Kingdom.
Leigh IM; Division of Cancer Research, School of Medicine, University of Dundee, Dundee, United Kingdom; Institute of Dentistry, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.
Saville MK; Division of Cancer Research, School of Medicine, University of Dundee, Dundee, United Kingdom. Electronic address: m.k.saville@dundee.ac.uk.

J Invest Dermatol ; 140(6): 1154-1165.e5, 2020 06.

Article em En | MEDLINE | ID: mdl-31705877

Assuntos

Carcinoma de Células Escamosas/tratamento farmacológico; Neoplasias Cutâneas/tratamento farmacológico; Carcinoma de Células Escamosas/patologia; Proteínas de Ciclo Celular/antagonistas & inibidores; Proteínas de Ciclo Celular/genética; Proteínas de Ciclo Celular/metabolismo; Linhagem Celular Tumoral; Ciclopentanos/farmacologia; Ciclopentanos/uso terapêutico; Ensaios de Seleção de Medicamentos Antitumorais; Endopeptidases/genética; Endopeptidases/metabolismo; Complexos Endossomais de Distribuição Requeridos para Transporte/antagonistas & inibidores; Complexos Endossomais de Distribuição Requeridos para Transporte/genética; Complexos Endossomais de Distribuição Requeridos para Transporte/metabolismo; Proteínas F-Box/antagonistas & inibidores; Proteínas F-Box/genética; Proteínas F-Box/metabolismo; Técnicas de Silenciamento de Genes; Humanos; Terapia de Alvo Molecular/métodos; Proteínas Nucleares/antagonistas & inibidores; Proteínas Nucleares/genética; Proteínas Nucleares/metabolismo; Pirimidinas/farmacologia; Pirimidinas/uso terapêutico; RNA Interferente Pequeno/metabolismo; Neoplasias Cutâneas/patologia; Ubiquitina Tiolesterase/antagonistas & inibidores; Ubiquitina Tiolesterase/genética; Ubiquitina Tiolesterase/metabolismo; Enzimas Ativadoras de Ubiquitina/antagonistas & inibidores; Enzimas Ativadoras de Ubiquitina/genética; Enzimas Ativadoras de Ubiquitina/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Carcinoma de Células Escamosas Tipo de estudo: Diagnostic_studies / Prognostic_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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