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Safety, pharmacokinetics, and antiviral effects of ABI-H0731, a hepatitis B virus core inhibitor: a randomised, placebo-controlled phase 1 trial.
Yuen, Man-Fung; Agarwal, Kosh; Gane, Edward J; Schwabe, Christian; Ahn, Sang Hoon; Kim, Dong Joon; Lim, Young-Suk; Cheng, Wendy; Sievert, William; Visvanathan, Kumar; Ruby, Eric; Liaw, Sandy; Yan, Ran; Huang, Qi; Colonno, Richard; Lopatin, Uri.
Afiliação
  • Yuen MF; Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region, China. Electronic address: mfyuen@hkucc.hku.hk.
  • Agarwal K; Institute of Liver Studies, King's College Hospital, London, UK.
  • Gane EJ; Auckland Clinical Studies, Auckland, New Zealand.
  • Schwabe C; Auckland Clinical Studies, Auckland, New Zealand.
  • Ahn SH; Severance Hospital, Seoul, South Korea.
  • Kim DJ; Hallym University, Chuncheon Sacred Heart Hospital, Gangwon-do, South Korea.
  • Lim YS; Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
  • Cheng W; Linear Clinical Research, Perth, WA, Australia.
  • Sievert W; Monash Health, Monash University, VIC, Australia.
  • Visvanathan K; St Vincent's Hospital, Department of Medicine, University of Melbourne, Melbourne, VIC, Australia.
  • Ruby E; Assembly Biosciences, San Francisco, CA, USA.
  • Liaw S; Assembly Biosciences, San Francisco, CA, USA.
  • Yan R; Assembly Biosciences, San Francisco, CA, USA.
  • Huang Q; Assembly Biosciences, San Francisco, CA, USA.
  • Colonno R; Assembly Biosciences, San Francisco, CA, USA.
  • Lopatin U; Assembly Biosciences, San Francisco, CA, USA.
Lancet Gastroenterol Hepatol ; 5(2): 152-166, 2020 02.
Article em En | MEDLINE | ID: mdl-31711752
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Proteínas do Core Viral / Vírus da Hepatite B / Hepatite B Crônica / Antígenos E da Hepatite B Tipo de estudo: Observational_studies / Prognostic_studies Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Proteínas do Core Viral / Vírus da Hepatite B / Hepatite B Crônica / Antígenos E da Hepatite B Tipo de estudo: Observational_studies / Prognostic_studies Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article