Neurophysiological aftereffects of 10â¯Hz and 20â¯Hz transcranial alternating current stimulation over bilateral sensorimotor cortex.
Brain Res
; 1727: 146542, 2020 01 15.
Article
em En
| MEDLINE
| ID: mdl-31712086
ABSTRACT
Alpha (8-12â¯Hz) and beta (13-30â¯Hz) oscillations are believed to be involved in motor control. Their modulation with transcranial alternating current stimulation (tACS) has been shown to alter motor behavior and cortical excitability. The aim of the present study was to determine whether tACS applied bilaterally over sensorimotor cortex at 10â¯Hz and 20â¯Hz modulates interhemispheric interactions and corticospinal excitability. Thirty healthy volunteers participated in a randomized, cross-over, sham-controlled, double-blind protocol. Sham and active tACS (10â¯Hz, 20â¯Hz, 1â¯mA) were applied for 20â¯min over bilateral sensorimotor areas. The physiological effects of tACS on corticospinal excitability and interhemispheric inhibition were assessed with transcranial magnetic stimulation. Physiological mirror movements were assessed to measure the overflow of motor activity to the contralateral M1 during voluntary muscle contraction. Bilateral 10â¯Hz tACS reduced corticospinal excitability. There was no significant effect of tACS on physiological mirror movements and interhemispheric inhibition. Ten Hz tACS was associated with response patterns consistent with corticospinal inhibition in 57% of participants. The present results indicate that application of tACS at the alpha frequency can induce aftereffects in sensorimotor cortex of healthy individuals.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Desempenho Psicomotor
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Tratos Piramidais
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Córtex Sensório-Motor
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Estimulação Transcraniana por Corrente Contínua
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Excitabilidade Cortical
Tipo de estudo:
Clinical_trials
Limite:
Adolescent
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Adult
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Female
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Humans
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Male
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article