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Dimethyl fumarate dampens IL-17-ACT1-TBK1 axis-mediated phosphorylation of Regnase-1 and suppresses IL-17-induced IκB-ζ expression.
Ohgakiuchi, Yui; Saino, Yuka; Muromoto, Ryuta; Komori, Yuki; Sato, Ami; Hirashima, Koki; Kitai, Yuichi; Kashiwakura, Jun-Ichi; Oritani, Kenji; Matsuda, Tadashi.
Afiliação
  • Ohgakiuchi Y; Department of Immunology, Graduate School of Pharmaceutical Sciences Hokkaido University, Sapporo, 060-0812, Japan.
  • Saino Y; Department of Immunology, Graduate School of Pharmaceutical Sciences Hokkaido University, Sapporo, 060-0812, Japan.
  • Muromoto R; Department of Immunology, Graduate School of Pharmaceutical Sciences Hokkaido University, Sapporo, 060-0812, Japan. Electronic address: muro@pharm.hokudai.ac.jp.
  • Komori Y; Department of Immunology, Graduate School of Pharmaceutical Sciences Hokkaido University, Sapporo, 060-0812, Japan.
  • Sato A; Department of Immunology, Graduate School of Pharmaceutical Sciences Hokkaido University, Sapporo, 060-0812, Japan.
  • Hirashima K; Department of Immunology, Graduate School of Pharmaceutical Sciences Hokkaido University, Sapporo, 060-0812, Japan.
  • Kitai Y; Department of Immunology, Graduate School of Pharmaceutical Sciences Hokkaido University, Sapporo, 060-0812, Japan.
  • Kashiwakura JI; Department of Immunology, Graduate School of Pharmaceutical Sciences Hokkaido University, Sapporo, 060-0812, Japan.
  • Oritani K; Department of Hematology, International University of Health and Welfare, 4-3 Kouzunomori, Narita, Chiba, 286-8686, Japan.
  • Matsuda T; Department of Immunology, Graduate School of Pharmaceutical Sciences Hokkaido University, Sapporo, 060-0812, Japan. Electronic address: tmatsuda@pharm.hokudai.ac.jp.
Biochem Biophys Res Commun ; 521(4): 957-963, 2020 01 22.
Article em En | MEDLINE | ID: mdl-31718798
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ribonucleases / Regulação da Expressão Gênica / Proteínas Serina-Treonina Quinases / Interleucina-17 / Proteínas Adaptadoras de Transdução de Sinal / Fumarato de Dimetilo Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ribonucleases / Regulação da Expressão Gênica / Proteínas Serina-Treonina Quinases / Interleucina-17 / Proteínas Adaptadoras de Transdução de Sinal / Fumarato de Dimetilo Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article