Promoter hypermethylation of the CFTR gene as a novel diagnostic and prognostic marker of breast cancer.

Liu, Kaisheng; Dong, Fajin; Gao, Hengyuan; Guo, Yaomin; Li, Haili; Yang, Fang; Zhao, Pan; Dai, Yong; Wang, Jianhong; Zhou, Wenbin; Zou, Chang

Liu, Kaisheng; Dong, Fajin; Gao, Hengyuan; Guo, Yaomin; Li, Haili; Yang, Fang; Zhao, Pan; Dai, Yong; Wang, Jianhong; Zhou, Wenbin; Zou, Chang.

Afiliação

Liu K; The First Affiliated Hospital of Southern University of Science and Technology, The Second Clinical Medical College of Jinan University, Shenzhen People's Hospital, Shenzhen, 518020, Guangdong, China.
Dong F; The First Affiliated Hospital of Southern University of Science and Technology, The Second Clinical Medical College of Jinan University, Shenzhen People's Hospital, Shenzhen, 518020, Guangdong, China.
Gao H; The First Affiliated Hospital of Southern University of Science and Technology, The Second Clinical Medical College of Jinan University, Shenzhen People's Hospital, Shenzhen, 518020, Guangdong, China.
Guo Y; The First Affiliated Hospital of Southern University of Science and Technology, The Second Clinical Medical College of Jinan University, Shenzhen People's Hospital, Shenzhen, 518020, Guangdong, China.
Li H; The First Affiliated Hospital of Southern University of Science and Technology, The Second Clinical Medical College of Jinan University, Shenzhen People's Hospital, Shenzhen, 518020, Guangdong, China.
Yang F; The First Affiliated Hospital of Southern University of Science and Technology, The Second Clinical Medical College of Jinan University, Shenzhen People's Hospital, Shenzhen, 518020, Guangdong, China.
Zhao P; The First Affiliated Hospital of Southern University of Science and Technology, The Second Clinical Medical College of Jinan University, Shenzhen People's Hospital, Shenzhen, 518020, Guangdong, China.
Dai Y; The First Affiliated Hospital of Southern University of Science and Technology, The Second Clinical Medical College of Jinan University, Shenzhen People's Hospital, Shenzhen, 518020, Guangdong, China.
Wang J; The First Affiliated Hospital of Southern University of Science and Technology, The Second Clinical Medical College of Jinan University, Shenzhen People's Hospital, Shenzhen, 518020, Guangdong, China.
Zhou W; The First Affiliated Hospital of Southern University of Science and Technology, The Second Clinical Medical College of Jinan University, Shenzhen People's Hospital, Shenzhen, 518020, Guangdong, China.
Zou C; The First Affiliated Hospital of Southern University of Science and Technology, The Second Clinical Medical College of Jinan University, Shenzhen People's Hospital, Shenzhen, 518020, Guangdong, China.

Cell Biol Int ; 44(2): 603-609, 2020 Feb.

Article em En | MEDLINE | ID: mdl-31721358

Assuntos

Biomarcadores Tumorais/genética; Neoplasias da Mama/patologia; Regulador de Condutância Transmembrana em Fibrose Cística/genética; Metilação de DNA; Regulação Neoplásica da Expressão Gênica; Regiões Promotoras Genéticas; Apoptose; Neoplasias da Mama/genética; Neoplasias da Mama/metabolismo; Proliferação de Células; Regulador de Condutância Transmembrana em Fibrose Cística/metabolismo; Feminino; Humanos; Invasividade Neoplásica; Prognóstico; Taxa de Sobrevida; Análise Serial de Tecidos; Células Tumorais Cultivadas

Palavras-chave

CFTR; biomarker; breast cancer; methylation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Biomarcadores Tumorais / Regulação Neoplásica da Expressão Gênica / Regiões Promotoras Genéticas / Regulador de Condutância Transmembrana em Fibrose Cística / Metilação de DNA Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Female / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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