Chloroacetaldehyde reacts with Z-DNA.
J Mol Biol
; 201(4): 773-6, 1988 Jun 20.
Article
em En
| MEDLINE
| ID: mdl-3172205
ABSTRACT
We show that chloroacetaldehyde, a chemical compound known to be reactive with unpaired adenine and cytosine residues, reacts with adenine residues (syn conformation) but not with cytosine residues (anti conformation) within Z-DNA. These modified residues are sensitive to cleavage by piperidine, which allows mapping at the single nucleotide level.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
DNA
/
Acetaldeído
Idioma:
En
Ano de publicação:
1988
Tipo de documento:
Article