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The repositioning of epigenetic probes/inhibitors identifies new anti-schistosomal lead compounds and chemotherapeutic targets.
Whatley, Kezia C L; Padalino, Gilda; Whiteland, Helen; Geyer, Kathrin K; Hulme, Benjamin J; Chalmers, Iain W; Forde-Thomas, Josephine; Ferla, Salvatore; Brancale, Andrea; Hoffmann, Karl F.
Afiliação
  • Whatley KCL; Institute of Biological, Environmental and Rural Sciences (IBERS), Aberystwyth University, Aberystwyth, United Kingdom.
  • Padalino G; Institute of Biological, Environmental and Rural Sciences (IBERS), Aberystwyth University, Aberystwyth, United Kingdom.
  • Whiteland H; Institute of Biological, Environmental and Rural Sciences (IBERS), Aberystwyth University, Aberystwyth, United Kingdom.
  • Geyer KK; Institute of Biological, Environmental and Rural Sciences (IBERS), Aberystwyth University, Aberystwyth, United Kingdom.
  • Hulme BJ; Institute of Biological, Environmental and Rural Sciences (IBERS), Aberystwyth University, Aberystwyth, United Kingdom.
  • Chalmers IW; Institute of Biological, Environmental and Rural Sciences (IBERS), Aberystwyth University, Aberystwyth, United Kingdom.
  • Forde-Thomas J; Institute of Biological, Environmental and Rural Sciences (IBERS), Aberystwyth University, Aberystwyth, United Kingdom.
  • Ferla S; School of Pharmacy and Pharmaceutical Sciences, Cardiff University, King Edward VII Avenue, Cardiff, United Kingdom.
  • Brancale A; School of Pharmacy and Pharmaceutical Sciences, Cardiff University, King Edward VII Avenue, Cardiff, United Kingdom.
  • Hoffmann KF; Institute of Biological, Environmental and Rural Sciences (IBERS), Aberystwyth University, Aberystwyth, United Kingdom.
PLoS Negl Trop Dis ; 13(11): e0007693, 2019 11.
Article em En | MEDLINE | ID: mdl-31730617

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Schistosomatidae / Esquistossomose / Epigênese Genética / Reposicionamento de Medicamentos / Chumbo Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Schistosomatidae / Esquistossomose / Epigênese Genética / Reposicionamento de Medicamentos / Chumbo Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article