The Role of Non-coding RNAs in Oncology.
Cell
; 179(5): 1033-1055, 2019 11 14.
Article
em En
| MEDLINE
| ID: mdl-31730848
For decades, research into cancer biology focused on the involvement of protein-coding genes. Only recently was it discovered that an entire class of molecules, termed non-coding RNA (ncRNA), plays key regulatory roles in shaping cellular activity. An explosion of studies into ncRNA biology has since shown that they represent a diverse and prevalent group of RNAs, including both oncogenic molecules and those that work in a tumor suppressive manner. As a result, hundreds of cancer-focused clinical trials involving ncRNAs as novel biomarkers or therapies have begun and these are likely just the beginning.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
RNA não Traduzido
/
Oncologia
Limite:
Humans
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article