Vildagliptin, a DPP-4 Inhibitor, Attenuates Endothelial Dysfunction and Atherogenesis in Nondiabetic Apolipoprotein E-Deficient Mice.

Aini, Kunduziayi; Fukuda, Daiju; Tanaka, Kimie; Higashikuni, Yasutomi; Hirata, Yoichiro; Yagi, Shusuke; Kusunose, Kenya; Yamada, Hirotsugu; Soeki, Takeshi; Sata, Masataka

Aini, Kunduziayi; Fukuda, Daiju; Tanaka, Kimie; Higashikuni, Yasutomi; Hirata, Yoichiro; Yagi, Shusuke; Kusunose, Kenya; Yamada, Hirotsugu; Soeki, Takeshi; Sata, Masataka.

Afiliação

Aini K; Department of Cardiovascular Medicine, Tokushima University Graduate School of Biomedical Sciences.
Fukuda D; Department of Cardio-Diabetes Medicine, Tokushima University Graduate School of Biomedical Science.
Tanaka K; Division for Health Service Promotion, The University of Tokyo.
Higashikuni Y; Department of Cardiovascular Medicine, The University of Tokyo.
Hirata Y; Department of Pediatrics, The University of Tokyo Hospital.
Yagi S; Department of Cardiovascular Medicine, Tokushima University Graduate School of Biomedical Sciences.
Kusunose K; Department of Cardiovascular Medicine, Tokushima University Graduate School of Biomedical Sciences.
Yamada H; Department of Community Medicine for Cardiology, Tokushima University Graduate School of Biomedical Sciences.
Soeki T; Department of Cardiovascular Medicine, Tokushima University Graduate School of Biomedical Sciences.
Sata M; Department of Cardiovascular Medicine, Tokushima University Graduate School of Biomedical Sciences.

Int Heart J ; 60(6): 1421-1429, 2019 Nov 30.

Article em En | MEDLINE | ID: mdl-31735774

Assuntos

Aterosclerose/prevenção & controle; Inibidores da Dipeptidil Peptidase IV/uso terapêutico; Células Endoteliais/efeitos dos fármacos; Endotélio Vascular/efeitos dos fármacos; Vildagliptina/uso terapêutico; Animais; Apolipoproteínas E; Aterosclerose/etiologia; Aterosclerose/patologia; Técnicas de Cultura de Células; Modelos Animais de Doenças; Células Endoteliais/fisiologia; Endotélio Vascular/patologia; Camundongos; Camundongos Endogâmicos C57BL; Molécula 1 de Adesão de Célula Vascular/sangue

Palavras-chave

Atherosclerosis; Diabetes mellitus; Endothelial function; GLP-1

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Endotélio Vascular / Células Endoteliais / Aterosclerose / Inibidores da Dipeptidil Peptidase IV / Vildagliptina Tipo de estudo: Etiology_studies / Guideline Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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