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Update 2020: nomenclature and listing of celiac disease-relevant gluten epitopes recognized by CD4+ T cells.
Sollid, Ludvig M; Tye-Din, Jason A; Qiao, Shuo-Wang; Anderson, Robert P; Gianfrani, Carmen; Koning, Frits.
Afiliação
  • Sollid LM; KG Jebsen Coeliac Disease Research Centre and Department of Immunology, Oslo University Hospital, Rikshospitalet, University of Oslo, Oslo, Norway. l.m.sollid@medisin.uio.no.
  • Tye-Din JA; Immunology Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.
  • Qiao SW; KG Jebsen Coeliac Disease Research Centre and Department of Immunology, Oslo University Hospital, Rikshospitalet, University of Oslo, Oslo, Norway.
  • Anderson RP; Immunology Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.
  • Gianfrani C; Institute of Biochemistry and Cell Biology, National Research Council of Italy, Naples, Italy.
  • Koning F; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands.
Immunogenetics ; 72(1-2): 85-88, 2020 02.
Article em En | MEDLINE | ID: mdl-31735991
Celiac disease is caused by an abnormal intestinal T cell response to cereal gluten proteins. The disease has a strong human leukocyte antigen (HLA) association, and CD4+ T cells recognizing gluten epitopes presented by disease-associated HLA-DQ allotypes are considered to be drivers of the disease. This paper provides an update of the currently known HLA-DQ restricted gluten T cell epitopes with their names and sequences.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T CD4-Positivos / Doença Celíaca / Epitopos de Linfócito T / Glutens / Complexo Principal de Histocompatibilidade Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T CD4-Positivos / Doença Celíaca / Epitopos de Linfócito T / Glutens / Complexo Principal de Histocompatibilidade Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article