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Assessment of nanomaterial-induced hepatotoxicity using a 3D human primary multi-cellular microtissue exposed repeatedly over 21 days - the suitability of the in vitro system as an in vivo surrogate.
Kermanizadeh, Ali; Berthing, Trine; Guzniczak, Ewa; Wheeldon, Melanie; Whyte, Graeme; Vogel, Ulla; Moritz, Wolfgang; Stone, Vicki.
Afiliação
  • Kermanizadeh A; Heriot Watt University, School of Engineering and Physical Sciences, Edinburgh, UK. Ali.Kermanizadeh@hw.ac.uk.
  • Berthing T; National Research Centre for the Working Environment, Copenhagen, Denmark.
  • Guzniczak E; Heriot Watt University, School of Engineering and Physical Sciences, Edinburgh, UK.
  • Wheeldon M; Heriot Watt University, School of Engineering and Physical Sciences, Edinburgh, UK.
  • Whyte G; Heriot Watt University, School of Engineering and Physical Sciences, Edinburgh, UK.
  • Vogel U; National Research Centre for the Working Environment, Copenhagen, Denmark.
  • Moritz W; InSphero AG, Wagistrasse 27, Schlieren, Switzerland.
  • Stone V; Heriot Watt University, School of Engineering and Physical Sciences, Edinburgh, UK.
Part Fibre Toxicol ; 16(1): 42, 2019 11 19.
Article em En | MEDLINE | ID: mdl-31739797
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hepatócitos / Técnicas de Cultura de Tecidos / Nanoestruturas / Doença Hepática Induzida por Substâncias e Drogas / Células de Kupffer / Fígado Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hepatócitos / Técnicas de Cultura de Tecidos / Nanoestruturas / Doença Hepática Induzida por Substâncias e Drogas / Células de Kupffer / Fígado Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article