Myocarditis as a lupus challenge: two case reports.
J Med Case Rep
; 13(1): 343, 2019 Nov 20.
Article
em En
| MEDLINE
| ID: mdl-31744544
ABSTRACT
BACKGROUND:
Myocarditis is an uncommon manifestation of systemic lupus erythematosus in which the clinical presentation can range from subclinical to life-threatening. We report cases of two patients who presented to our hospital with myocarditis as an initial manifestation of systemic lupus erythematosus despite negative results of extensive workup that excluded other diagnoses. The mainstays of treatment are corticosteroids, immunosuppressive agents, and anti-heart failure medications, with use of the latter being case-specific. Mycophenolate mofetil was the cornerstone of the proposed treatment for induction of remission, although it is well known to be used as a maintenance therapy in lupus myocarditis. CASE PRESENTATION Both Emirati patients described satisfied the diagnostic criteria for mixed connective tissue disease (systemic lupus predominant) and systemic lupus erythematous. Other differential diagnoses of myocarditis were excluded. The patients were started on pulsed steroid followed by oral steroid, with hydroxychloroquine, mycophenolate mofetil, and anti-heart failure medications used as needed. Dramatic responses were noted in the first few weeks in terms of symptoms.CONCLUSION:
Early recognition and treatment of lupus myocarditis is needed to avoid fatal consequences.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Corticosteroides
/
Hidroxicloroquina
/
Imunossupressores
/
Lúpus Eritematoso Sistêmico
/
Ácido Micofenólico
/
Miocardite
Tipo de estudo:
Etiology_studies
Limite:
Adult
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Female
/
Humans
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article