Downregulation of microR-147b represses the proliferation and invasion of thyroid carcinoma cells by inhibiting Wnt/ß-catenin signaling via targeting SOX15.

Xu, Chongwen; Liu, Junsong; Yao, Xiaobao; Bai, Yanxia; Zhao, Qian; Zhao, Ruimin; Kou, Bo; Li, Honghui; Han, Peng; Wang, Xuan; Guo, Longwei; Zheng, Zhiwei; Zhang, Shaoqiang

Xu, Chongwen; Liu, Junsong; Yao, Xiaobao; Bai, Yanxia; Zhao, Qian; Zhao, Ruimin; Kou, Bo; Li, Honghui; Han, Peng; Wang, Xuan; Guo, Longwei; Zheng, Zhiwei; Zhang, Shaoqiang.

Afiliação

Xu C; Department of Otorhinolaryngology-Head and Neck Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi Province, China.
Liu J; Department of Otorhinolaryngology-Head and Neck Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi Province, China.
Yao X; Department of Otorhinolaryngology-Head and Neck Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi Province, China.
Bai Y; Department of Otorhinolaryngology-Head and Neck Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi Province, China.
Zhao Q; Department of Otorhinolaryngology-Head and Neck Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi Province, China.
Zhao R; Department of Otorhinolaryngology-Head and Neck Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi Province, China.
Kou B; Department of Otorhinolaryngology-Head and Neck Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi Province, China.
Li H; Department of Otorhinolaryngology-Head and Neck Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi Province, China.
Han P; Department of Otorhinolaryngology-Head and Neck Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi Province, China.
Wang X; Department of Otorhinolaryngology-Head and Neck Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi Province, China.
Guo L; Department of Radiation Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi Province, China.
Zheng Z; The Third Ward of Department of General Surgery, Rizhao People's Hospital, Rizhao City, 276800, Shandong Province, China. Electronic address: zheng_zhiweizw@163.com.
Zhang S; Department of Otorhinolaryngology-Head and Neck Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi Province, China. Electronic address: zhangentsq@163.com.

Mol Cell Endocrinol ; 501: 110662, 2020 02 05.

Article em En | MEDLINE | ID: mdl-31760045

Assuntos

Proliferação de Células/genética; Regulação para Baixo/genética; MicroRNAs/genética; Invasividade Neoplásica/genética; Fatores de Transcrição SOX/genética; Neoplasias da Glândula Tireoide/genética; Via de Sinalização Wnt/genética; beta Catenina/genética; Regiões 3' não Traduzidas/genética; Animais; Linhagem Celular Tumoral; Movimento Celular/genética; Regulação Neoplásica da Expressão Gênica/genética; Células HEK293; Humanos; Masculino; Camundongos; Camundongos Endogâmicos BALB C; Camundongos Nus; Regulação para Cima/genética

Palavras-chave

SOX15; Thyroid carcinoma; Wnt; miR-147b

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Glândula Tireoide / Regulação para Baixo / MicroRNAs / Proliferação de Células / Beta Catenina / Fatores de Transcrição SOX / Via de Sinalização Wnt / Invasividade Neoplásica Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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