Safety of Food Oral Immunotherapy: What We Know, and What We Need to Learn.
Immunol Allergy Clin North Am
; 40(1): 111-133, 2020 02.
Article
em En
| MEDLINE
| ID: mdl-31761113
ABSTRACT
Oral immunotherapy (OIT) for food allergy entails a risk of adverse reactions, including anaphylaxis. This safety concern is the major barrier for OIT to become a therapeutic option in clinical practice. The high heterogeneity in safety reporting of OIT studies prevents setting the safety profile accurately. An international consensus is needed to facilitate the analysis of large pooled clinical data with homogeneous safety reporting, that together with integrated omics, and patients/families' opinions, may help stratify the patients' risk and needs, and help developing safe(r) individualized care pathways. This will give OIT the right place in the food allergy therapy.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Dessensibilização Imunológica
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Hipersensibilidade Alimentar
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Anafilaxia
Tipo de estudo:
Etiology_studies
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Guideline
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Risk_factors_studies
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article