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A structural basis for antibody-mediated neutralization of Nipah virus reveals a site of vulnerability at the fusion glycoprotein apex.
Avanzato, Victoria A; Oguntuyo, Kasopefoluwa Y; Escalera-Zamudio, Marina; Gutierrez, Bernardo; Golden, Michael; Kosakovsky Pond, Sergei L; Pryce, Rhys; Walter, Thomas S; Seow, Jeffrey; Doores, Katie J; Pybus, Oliver G; Munster, Vincent J; Lee, Benhur; Bowden, Thomas A.
Afiliação
  • Avanzato VA; Division of Structural Biology, Wellcome Center for Human Genetics, University of Oxford, OX3 7BN Oxford, United Kingdom.
  • Oguntuyo KY; Laboratory of Virology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840.
  • Escalera-Zamudio M; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029.
  • Gutierrez B; Department of Zoology, Oxford University, OX1 3PS Oxford, United Kingdom.
  • Golden M; Department of Zoology, Oxford University, OX1 3PS Oxford, United Kingdom.
  • Kosakovsky Pond SL; Department of Zoology, Oxford University, OX1 3PS Oxford, United Kingdom.
  • Pryce R; Institute for Genomics and Evolutionary Medicine, Temple University, Philadelphia, PA 19122.
  • Walter TS; Division of Structural Biology, Wellcome Center for Human Genetics, University of Oxford, OX3 7BN Oxford, United Kingdom.
  • Seow J; Division of Structural Biology, Wellcome Center for Human Genetics, University of Oxford, OX3 7BN Oxford, United Kingdom.
  • Doores KJ; Department of Infectious Diseases, King's College London, Guy's Hospital, SE1 9RT London, United Kingdom.
  • Pybus OG; Department of Infectious Diseases, King's College London, Guy's Hospital, SE1 9RT London, United Kingdom.
  • Munster VJ; Department of Zoology, Oxford University, OX1 3PS Oxford, United Kingdom.
  • Lee B; Laboratory of Virology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840.
  • Bowden TA; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029; Benhur.Lee@mssm.edu thomas.bowden@strubi.ox.ac.uk.
Proc Natl Acad Sci U S A ; 116(50): 25057-25067, 2019 12 10.
Article em En | MEDLINE | ID: mdl-31767754

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Virais de Fusão / Vírus Hendra / Internalização do Vírus / Anticorpos Neutralizantes Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Virais de Fusão / Vírus Hendra / Internalização do Vírus / Anticorpos Neutralizantes Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article