Structure activity relationship, 6-modified purine riboside analogues to activate hSTING, stimulator of interferon genes.

Bonnac, Laurent F; Dreis, Christine D; Geraghty, Robert J

Bonnac, Laurent F; Dreis, Christine D; Geraghty, Robert J.

Afiliação

Bonnac LF; Center for Drug Design, College of Pharmacy, University of Minnesota, NHH, 312 Church St SE, Minneapolis, MN 55455, USA. Electronic address: bonna008@umn.edu.
Dreis CD; Center for Drug Design, College of Pharmacy, University of Minnesota, NHH, 312 Church St SE, Minneapolis, MN 55455, USA.
Geraghty RJ; Center for Drug Design, College of Pharmacy, University of Minnesota, NHH, 312 Church St SE, Minneapolis, MN 55455, USA.

Bioorg Med Chem Lett ; 30(2): 126819, 2020 01 15.

Article em En | MEDLINE | ID: mdl-31780305

Assuntos

Interferons/química; Purinas/química; Humanos; Estrutura Molecular; Relação Estrutura-Atividade

Palavras-chave

Cell based assay; Innate immune response; Interferons; Nucleoside analogues; hSTING activation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Purinas / Interferons Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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