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O-acetyl sialomucin and differentiation of stomach cancer: a histochemical study.
Huang, C B; Xu, J A; Wu, K R; Wang, W M.
Afiliação
  • Huang CB; Department of Pathological Anatomy, Zunyi Medical College, P.R. China.
Anticancer Res ; 8(4): 829-32, 1988.
Article em En | MEDLINE | ID: mdl-3178173
In one hundred surgical specimens with stomach cancer, 78 cases contained intestinal metaplasia (IM) in the outer margin mucosa nearby carcinoma focus, while the remaining 22 had no IM. IM was histochemically classified into small intestinal type, sulphomucin colonic type (S), O-acetyl sialo-sulphomucin colonic type (OS) and O-acetyl sialomucin colonic type (O). The incidence of OS and O in well differentiated carcinoma (WCa) (22/27) was obviously higher than in poorly and undifferentiated carcinomas (PUCa) (17/51) (X2 = 14.5011, P less than 0.001). This suggests that O-acetyl sialomucin in IM may be correlated with the differentiation of gastric cancer, that is, OS may often be transformed into WCa if malignant change of IM occurs.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / Mucinas Limite: Humans Idioma: En Ano de publicação: 1988 Tipo de documento: Article
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / Mucinas Limite: Humans Idioma: En Ano de publicação: 1988 Tipo de documento: Article