Selective modification of a native protein in a patient tissue homogenate using palladium nanoparticles.
Chem Commun (Camb)
; 55(100): 15121-15124, 2019 Dec 28.
Article
em En
| MEDLINE
| ID: mdl-31782421
ABSTRACT
We have developed new benign palladium nanoparticles able to catalyze the Suzuki-Miyaura cross-coupling reaction on human thyroglobulin (Tg), a naturally iodinated protein produced by the thyroid gland, in homogenates from patients' tissues. This represents the first example of a chemoselective native protein modification using transition metal nanoobjects in near-organ medium.
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Coleções:
01-internacional
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MEDLINE
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article