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Single agent talacotuzumab demonstrates limited efficacy but considerable toxicity in elderly high-risk MDS or AML patients failing hypomethylating agents.
Kubasch, Anne Sophie; Schulze, Freya; Giagounidis, Aristoteles; Götze, Katharina S; Krönke, Jan; Sockel, Katja; Middeke, Jan Moritz; Chermat, Fatiha; Gloaguen, Silke; Puttrich, Martin; Weigt, Carmen; William, Doreen; Fenaux, Pierre; Schlenk, Richard F; Thiede, Christian; Stasik, Sebastian; Mies, Anna; Adès, Lionel; Oelschlägel, Uta; Platzbecker, Uwe.
Afiliação
  • Kubasch AS; Medical Clinic and Policlinic I, Hematology and Cellular Therapy, Leipzig University Hospital, Leipzig, Germany.
  • Schulze F; German MDS Study Group (D-MDS), Leipzig, Germany.
  • Giagounidis A; The European Myelodysplastic Syndromes Cooperative Group (EMSCO), Leipzig, Germany.
  • Götze KS; German MDS Study Group (D-MDS), Leipzig, Germany.
  • Krönke J; The European Myelodysplastic Syndromes Cooperative Group (EMSCO), Leipzig, Germany.
  • Sockel K; Department of Internal Medicine I, University Hospital Carl Gustav Carus Dresden, Dresden, Germany.
  • Middeke JM; German MDS Study Group (D-MDS), Leipzig, Germany.
  • Chermat F; The European Myelodysplastic Syndromes Cooperative Group (EMSCO), Leipzig, Germany.
  • Gloaguen S; Department for Oncology, Hematology and Palliative Care, Marien Hospital Düsseldorf, Düsseldorf, Germany.
  • Puttrich M; German MDS Study Group (D-MDS), Leipzig, Germany.
  • Weigt C; The European Myelodysplastic Syndromes Cooperative Group (EMSCO), Leipzig, Germany.
  • William D; Department of Medicine III, Klinikum rechts der Isar, TUM, Munich, Germany.
  • Fenaux P; German MDS Study Group (D-MDS), Leipzig, Germany.
  • Schlenk RF; The European Myelodysplastic Syndromes Cooperative Group (EMSCO), Leipzig, Germany.
  • Thiede C; Department of Internal Medicine III, University Hospital Ulm, Ulm, Germany.
  • Stasik S; German MDS Study Group (D-MDS), Leipzig, Germany.
  • Mies A; The European Myelodysplastic Syndromes Cooperative Group (EMSCO), Leipzig, Germany.
  • Adès L; Department of Internal Medicine I, University Hospital Carl Gustav Carus Dresden, Dresden, Germany.
  • Oelschlägel U; German MDS Study Group (D-MDS), Leipzig, Germany.
  • Platzbecker U; The European Myelodysplastic Syndromes Cooperative Group (EMSCO), Leipzig, Germany.
Leukemia ; 34(4): 1182-1186, 2020 04.
Article em En | MEDLINE | ID: mdl-31796915
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Azacitidina / Síndromes Mielodisplásicas / Resistencia a Medicamentos Antineoplásicos / Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos / Subunidade alfa de Receptor de Interleucina-3 / Anticorpos Monoclonais Tipo de estudo: Clinical_trials / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Aged80 / Female / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Azacitidina / Síndromes Mielodisplásicas / Resistencia a Medicamentos Antineoplásicos / Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos / Subunidade alfa de Receptor de Interleucina-3 / Anticorpos Monoclonais Tipo de estudo: Clinical_trials / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Aged80 / Female / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article