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The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs.
Akinc, Akin; Maier, Martin A; Manoharan, Muthiah; Fitzgerald, Kevin; Jayaraman, Muthusamy; Barros, Scott; Ansell, Steven; Du, Xinyao; Hope, Michael J; Madden, Thomas D; Mui, Barbara L; Semple, Sean C; Tam, Ying K; Ciufolini, Marco; Witzigmann, Dominik; Kulkarni, Jayesh A; van der Meel, Roy; Cullis, Pieter R.
Afiliação
  • Akinc A; Alnylam Pharmaceuticals, Cambridge, MA, USA.
  • Maier MA; Alnylam Pharmaceuticals, Cambridge, MA, USA.
  • Manoharan M; Alnylam Pharmaceuticals, Cambridge, MA, USA.
  • Fitzgerald K; Alnylam Pharmaceuticals, Cambridge, MA, USA.
  • Jayaraman M; Alnylam Pharmaceuticals, Cambridge, MA, USA.
  • Barros S; Alnylam Pharmaceuticals, Cambridge, MA, USA.
  • Ansell S; Acuitas Therapeutics, Vancouver, BC, Canada.
  • Du X; Acuitas Therapeutics, Vancouver, BC, Canada.
  • Hope MJ; Acuitas Therapeutics, Vancouver, BC, Canada.
  • Madden TD; Acuitas Therapeutics, Vancouver, BC, Canada.
  • Mui BL; Acuitas Therapeutics, Vancouver, BC, Canada.
  • Semple SC; Acuitas Therapeutics, Vancouver, BC, Canada.
  • Tam YK; Acuitas Therapeutics, Vancouver, BC, Canada.
  • Ciufolini M; University of British Columbia, Vancouver, BC, Canada.
  • Witzigmann D; University of British Columbia, Vancouver, BC, Canada.
  • Kulkarni JA; University of British Columbia, Vancouver, BC, Canada.
  • van der Meel R; University of British Columbia, Vancouver, BC, Canada.
  • Cullis PR; University of British Columbia, Vancouver, BC, Canada. pieterc@mail.ubc.ca.
Nat Nanotechnol ; 14(12): 1084-1087, 2019 12.
Article em En | MEDLINE | ID: mdl-31802031
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polineuropatias / RNA Interferente Pequeno Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polineuropatias / RNA Interferente Pequeno Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article