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Association of Borderline Intellectual Functioning and Adverse Childhood Experience with adult psychiatric morbidity. Findings from a British birth cohort.
Hassiotis, Angela; Brown, Emma; Harris, James; Helm, David; Munir, Kerim; Salvador-Carulla, Luis; Bertelli, Marco; Baghdadli, Amaria; Wieland, Jannelien; Novell-Alsina, Ramon; Cid, Jordi; Vergés, Laura; Martínez-Leal, Rafael; Mutluer, Tuba; Ismayilov, Fuad; Emerson, Eric.
Afiliação
  • Hassiotis A; Division of Psychiatry, University College London, 149 Tottenham Court Road, London, W1T 7NF, UK. a.hassiotis@ucl.ac.uk.
  • Brown E; Camden & Islington Foundation Trust, St Pancras Hospital, London, UK. a.hassiotis@ucl.ac.uk.
  • Harris J; Division of Psychiatry, University College London, 149 Tottenham Court Road, London, W1T 7NF, UK.
  • Helm D; Developmental Neuropsychiatry, Department of Psychiatry and Behavioral Sciences, Bloomberg Children's Center, The Johns Hopkins Hospital, Baltimore, MD, USA.
  • Munir K; Institute for Community Inclusion, Division of Developmental Medicine, Boston Children's Hospital, Boston, MA, USA.
  • Salvador-Carulla L; Institute for Community Inclusion, Division of Developmental Medicine, Boston Children's Hospital, Boston, MA, USA.
  • Bertelli M; Developmental Medicine Center, Division of Developmental Medicine, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA.
  • Baghdadli A; Centre for Mental Health Research, Australian National University, Acton, Australia.
  • Wieland J; CREA, Research and Clinical Centre, San Sebastiano Foundation, Florence, Italy.
  • Novell-Alsina R; Child and Adolescent Psychiatry Department, Montpellier Hospital University, Montpellier, France.
  • Cid J; Kristal Centre for Psychiatry and Intellectual Disability, Rivierduinen, Leiden, The Netherlands.
  • Vergés L; Mental Health and Intellectual Disability Specialized Service, Catalan Health Govenment. Martí i Julià Hospital, Girona, Spain.
  • Martínez-Leal R; Mental Health and Intellectual Disability Specialized Service, Catalan Health Govenment. Martí i Julià Hospital, Girona, Spain.
  • Mutluer T; Mental Health and Intellectual Disability Specialized Service, Catalan Health Govenment. Martí i Julià Hospital, Girona, Spain.
  • Ismayilov F; Intellectual Disability and Developmental Disorders Research Unit (UNIVIDD), Fundació Villablanca, IISPV, Universitat Rovira i Virgili, CIBERSAM, Reus, Spain.
  • Emerson E; Department of Child and Adolescent Psychiatry, Koc University Hospital, Istanbul, Turkey.
BMC Psychiatry ; 19(1): 387, 2019 12 05.
Article em En | MEDLINE | ID: mdl-31805899
ABSTRACT

BACKGROUND:

To examine whether Borderline Intellectual Functioning (BIF) and Adverse Childhood Experiences independently predict adult psychiatric morbidity.

METHODS:

We performed a secondary analysis of longitudinal data derived from the 1970 British Birth Cohort Study to examine whether BIF and Adverse Childhood Experiences independently predict adult mental distress as measured by the Malaise Inventory. Factor analysis was used to derive a proxy measure of IQ from cognitive testing at age 10 or 5. Variables that could be indicators of exposure to Adverse Childhood Experiences were identified and grouped into health related and socio-economic related adversity.

RESULTS:

Children with BIF were significantly more likely than their peers to have been exposed to Adverse Childhood Experiences (BIF mean 5.90, non-BIF mean 3.19; Mann-Whitney z = 31.74, p < 0.001). As adults, participants with BIF were significantly more likely to score above the cut-off on the Malaise Inventory. We found statistically significant relationships between the number of socio-economic Adverse Childhood Experiences and poorer adult psychiatric morbidity (r range 0.104-0.141, all p < 001). At all ages the indirect mediating effects of Adverse Childhood Experiences were significantly related to adult psychiatric morbidity.

CONCLUSIONS:

The relationship between BIF and adult psychiatric morbidity appears to be partially mediated by exposure to Adverse Childhood Experiences. Where possible, targeting Adverse Childhood Experiences through early detection, prevention and interventions may improve psychiatric morbidity in this population group.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sobreviventes Adultos de Maus-Tratos Infantis / Experiências Adversas da Infância / Transtornos Mentais / Deficiência Intelectual Tipo de estudo: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Limite: Adult / Female / Humans / Male País/Região como assunto: Europa Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sobreviventes Adultos de Maus-Tratos Infantis / Experiências Adversas da Infância / Transtornos Mentais / Deficiência Intelectual Tipo de estudo: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Limite: Adult / Female / Humans / Male País/Região como assunto: Europa Idioma: En Ano de publicação: 2019 Tipo de documento: Article