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An intronic FTO variant rs16952570 confers protection against thiopurine-induced myelotoxicities in multiethnic Asian IBD patients.
Chen, Sylvia; Tan, Wei Zhi; Sutiman, Natalia; Lim, Cindy; Lee, Sze Sing; Leong, Wai Fook; Tjai, Madeline; Wang, Chunyan; Kong, Chris San Choon; Chuah, Sai Wei; Schwender, Brian John; Chan, Webber; Shim, Hang Hock; Lim, Wee Chian; Khor, Chiea Chuen; Ling, Khoon Lin; Chowbay, Balram.
Afiliação
  • Chen S; Clinical Pharmacology Laboratory, National Cancer Centre, Singapore, Singapore.
  • Tan WZ; Clinical Pharmacology Laboratory, National Cancer Centre, Singapore, Singapore.
  • Sutiman N; Clinical Pharmacology, SingHealth, Singapore, Singapore.
  • Lim C; Biostatistics Unit, Clinical Trials & Epidemiology Sciences, National Cancer Centre, Singapore, Singapore.
  • Lee SS; Clinical Pharmacology Laboratory, National Cancer Centre, Singapore, Singapore.
  • Leong WF; Clinical Pharmacology, SingHealth, Singapore, Singapore.
  • Tjai M; Clinical Pharmacology, SingHealth, Singapore, Singapore.
  • Wang C; Clinical Pharmacology, SingHealth, Singapore, Singapore.
  • Kong CSC; Department of Gastroenterology & Hepatology, Singapore General Hospital, Singapore, Singapore.
  • Chuah SW; Department of General Medicine, Gastroenterology and Hepatology Service, Sengkang General Hospital, Singapore, Singapore.
  • Schwender BJ; Department of Gastroenterology & Hepatology, Singapore General Hospital, Singapore, Singapore.
  • Chan W; Department of Gastroenterology & Hepatology, Singapore General Hospital, Singapore, Singapore.
  • Shim HH; Tucker Medical, Singapore, Singapore.
  • Lim WC; Department of Gastroenterology & Hepatology, Singapore General Hospital, Singapore, Singapore.
  • Khor CC; Department of Gastroenterology & Hepatology, Singapore General Hospital, Singapore, Singapore.
  • Ling KL; Department of Gastroenterology, Tan Tock Seng Hospital, Singapore, Singapore.
  • Chowbay B; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.
Pharmacogenomics J ; 20(3): 505-515, 2020 06.
Article em En | MEDLINE | ID: mdl-31813937
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Azatioprina / Variação Genética / Íntrons / Doenças Inflamatórias Intestinais / Povo Asiático / Dioxigenase FTO Dependente de alfa-Cetoglutarato Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Azatioprina / Variação Genética / Íntrons / Doenças Inflamatórias Intestinais / Povo Asiático / Dioxigenase FTO Dependente de alfa-Cetoglutarato Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article