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Structure-Based Design, Synthesis, and Biological Evaluation of Triazole-Based smHDAC8 Inhibitors.
Kalinin, Dmitrii V; Jana, Sunit K; Pfafenrot, Maxim; Chakrabarti, Alokta; Melesina, Jelena; Shaik, Tajith B; Lancelot, Julien; Pierce, Raymond J; Sippl, Wolfgang; Romier, Christophe; Jung, Manfred; Holl, Ralph.
Afiliação
  • Kalinin DV; Department of Chemistry Institute of Organic Chemistry, University of Hamburg, Martin-Luther-King-Platz 6, 20146, Hamburg, Germany.
  • Jana SK; German Center for Infection Research (DZIF) partner site Hamburg-Lübeck-Borstel-Riems.
  • Pfafenrot M; Institute of Pharmaceutical and Medicinal Chemistry, University of Münster, Corrensstr. 48, 48149, Münster, Germany.
  • Chakrabarti A; Cells-in-Motion Cluster of Excellence (EXC 1003 - CiM), University of Münster, Schlossplatz 4, 48149, Münster, Germany.
  • Melesina J; Institute of Pharmaceutical and Medicinal Chemistry, University of Münster, Corrensstr. 48, 48149, Münster, Germany.
  • Shaik TB; NRW Graduate School of Chemistry, University of Münster, Wilhelm-Klemm-Str. 10, 48149, Münster, Germany.
  • Lancelot J; Institute of Pharmaceutical and Medicinal Chemistry, University of Münster, Corrensstr. 48, 48149, Münster, Germany.
  • Pierce RJ; Institute of Pharmaceutical Sciences, Albert-Ludwigs-Universität Freiburg, Albertstr. 25, 79104, Freiburg, Germany.
  • Sippl W; Institute of Pharmacy, Martin Luther University of Halle-Wittenberg, Wolfgang-Langenbeck Str. 4, 06120, Halle/Saale, Germany.
  • Romier C; Département de Biologie Structurale Intégrative Institut de Génétique et Biologie Moléculaire et Cellulaire (IGBMC), Université de Strasbourg, CNRS, INSERM, 1 rue Laurent Fries, 67404, Illkirch Cedex, France.
  • Jung M; Université de Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille U1019-UMR 8204-CIIL-Centre d'Infection et d'Immunité de Lille, 59000, Lille, France.
  • Holl R; Université de Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille U1019-UMR 8204-CIIL-Centre d'Infection et d'Immunité de Lille, 59000, Lille, France.
ChemMedChem ; 15(7): 571-584, 2020 04 03.
Article em En | MEDLINE | ID: mdl-31816172
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Schistosoma mansoni / Esquistossomose / Triazóis / Desenho de Fármacos / Inibidores de Histona Desacetilases / Histona Desacetilases Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Schistosoma mansoni / Esquistossomose / Triazóis / Desenho de Fármacos / Inibidores de Histona Desacetilases / Histona Desacetilases Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article