Structural Basis for Glycerol Efflux and Selectivity of Human Aquaporin 7.

de Maré, Sofia W; Venskutonyte, Raminta; Eltschkner, Sandra; de Groot, Bert L; Lindkvist-Petersson, Karin

de Maré, Sofia W; Venskutonyte, Raminta; Eltschkner, Sandra; de Groot, Bert L; Lindkvist-Petersson, Karin.

Afiliação

de Maré SW; Experimental Medical Science, Medical Structural Biology, BMC C13, Lund University, SE-221 84 Lund, Sweden.
Venskutonyte R; Experimental Medical Science, Medical Structural Biology, BMC C13, Lund University, SE-221 84 Lund, Sweden.
Eltschkner S; Experimental Medical Science, Medical Structural Biology, BMC C13, Lund University, SE-221 84 Lund, Sweden.
de Groot BL; Department of Theoretical and Computational Biophysics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.
Lindkvist-Petersson K; Experimental Medical Science, Medical Structural Biology, BMC C13, Lund University, SE-221 84 Lund, Sweden. Electronic address: karin.lindkvist@med.lu.se.

Structure ; 28(2): 215-222.e3, 2020 02 04.

Article em En | MEDLINE | ID: mdl-31831212

Assuntos

Aquaporinas/química; Aquaporinas/metabolismo; Glicerol/metabolismo; Transporte Biológico; Cristalografia por Raios X; Humanos; Modelos Moleculares; Simulação de Dinâmica Molecular; Estrutura Secundária de Proteína; Água/metabolismo

Palavras-chave

AQP7; X-ray structure; adipocyte; aquaglyceroporin; aquaporin 7; atomistic MD simulations; glycerol channel; water

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Aquaporinas / Glicerol Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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