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Impact of drug distribution into adipose on tissue function: The cholesteryl ester transfer protein (CETP) inhibitor anacetrapib as a test case.
Johns, Douglas G; Wang, Sheng-Ping; Rosa, Raymond; Hubert, James; Xu, Suoyu; Chen, Ying; Bateman, Thomas; Blaustein, Robert O.
Afiliação
  • Johns DG; Department of Translational Pharmacology Merck & Co., Inc. Kenilworth NJ USA.
  • Wang SP; Department of Cardiometabolic Diseases/Atherosclerosis Merck & Co., Inc. Kenilworth NJ USA.
  • Rosa R; Department of Cardiometabolic Diseases/Atherosclerosis Merck & Co., Inc. Kenilworth NJ USA.
  • Hubert J; Department of Cardiometabolic Diseases/Atherosclerosis Merck & Co., Inc. Kenilworth NJ USA.
  • Xu S; Department of Pharmacokinetics, Pharmacodynamics and Drug Metabolism Merck & Co., Inc. Kenilworth NJ USA.
  • Chen Y; Department of Cardiometabolic Diseases/Atherosclerosis Merck & Co., Inc. Kenilworth NJ USA.
  • Bateman T; Department of Pharmacokinetics, Pharmacodynamics and Drug Metabolism Merck & Co., Inc. Kenilworth NJ USA.
  • Blaustein RO; Department of Clinical Research Merck & Co., Inc. Kenilworth NJ USA.
Pharmacol Res Perspect ; 7(6): e00543, 2019 12.
Article em En | MEDLINE | ID: mdl-31832204
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxazolidinonas / Tecido Adiposo Branco / Hipolipemiantes / Obesidade Tipo de estudo: Etiology_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxazolidinonas / Tecido Adiposo Branco / Hipolipemiantes / Obesidade Tipo de estudo: Etiology_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article