Mutant lamins cause nuclear envelope rupture and DNA damage in skeletal muscle cells.

Earle, Ashley J; Kirby, Tyler J; Fedorchak, Gregory R; Isermann, Philipp; Patel, Jineet; Iruvanti, Sushruta; Moore, Steven A; Bonne, Gisèle; Wallrath, Lori L; Lammerding, Jan

Earle, Ashley J; Kirby, Tyler J; Fedorchak, Gregory R; Isermann, Philipp; Patel, Jineet; Iruvanti, Sushruta; Moore, Steven A; Bonne, Gisèle; Wallrath, Lori L; Lammerding, Jan.

Afiliação

Earle AJ; Meinig School of Biomedical Engineering & Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY, USA.
Kirby TJ; Meinig School of Biomedical Engineering & Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY, USA.
Fedorchak GR; Meinig School of Biomedical Engineering & Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY, USA.
Isermann P; Meinig School of Biomedical Engineering & Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY, USA.
Patel J; Meinig School of Biomedical Engineering & Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY, USA.
Iruvanti S; Meinig School of Biomedical Engineering & Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY, USA.
Moore SA; Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Bonne G; Sorbonne Université, Inserm UMRS 974, Center of Research in Myology, Association Institute of Myology, Paris, France.
Wallrath LL; Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Lammerding J; Meinig School of Biomedical Engineering & Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY, USA. jan.lammerding@cornell.edu.

Nat Mater ; 19(4): 464-473, 2020 04.

Article em En | MEDLINE | ID: mdl-31844279

Assuntos

Dano ao DNA; Lamina Tipo A; Distrofia Muscular Animal; Mutação; Miofibrilas; Membrana Nuclear; Animais; Lamina Tipo A/genética; Lamina Tipo A/metabolismo; Camundongos; Camundongos Knockout; Distrofia Muscular Animal/genética; Distrofia Muscular Animal/metabolismo; Distrofia Muscular Animal/patologia; Miofibrilas/metabolismo; Miofibrilas/patologia; Membrana Nuclear/genética; Membrana Nuclear/metabolismo; Membrana Nuclear/patologia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dano ao DNA / Lamina Tipo A / Distrofia Muscular Animal / Mutação / Miofibrilas / Membrana Nuclear Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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