Trajectory Taken by Dimeric Cu/Zn Superoxide Dismutase through the Protein Unfolding and Dissociation Landscape Is Modulated by Salt Bridge Formation.

McAlary, Luke; Harrison, Julian A; Aquilina, J Andrew; Fitzgerald, Steven P; Kelso, Celine; Benesch, Justin L P; Yerbury, Justin J

McAlary, Luke; Harrison, Julian A; Aquilina, J Andrew; Fitzgerald, Steven P; Kelso, Celine; Benesch, Justin L P; Yerbury, Justin J.

Afiliação

McAlary L; Illawarra Health and Medical Research Institute , Wollongong , New South Wales 2522 , Australia.
Harrison JA; Molecular Horizons and School of Chemistry and Molecular Bioscience, Faculty of Science, Medicine and Health , University of Wollongong , Wollongong , New South Wales 2522 , Australia.
Aquilina JA; Molecular Horizons and School of Chemistry and Molecular Bioscience, Faculty of Science, Medicine and Health , University of Wollongong , Wollongong , New South Wales 2522 , Australia.
Fitzgerald SP; Illawarra Health and Medical Research Institute , Wollongong , New South Wales 2522 , Australia.
Kelso C; Molecular Horizons and School of Chemistry and Molecular Bioscience, Faculty of Science, Medicine and Health , University of Wollongong , Wollongong , New South Wales 2522 , Australia.
Benesch JLP; Department of Applied Mathematics , University of Leeds , Leeds LS2 9JT , U.K.
Yerbury JJ; Molecular Horizons and School of Chemistry and Molecular Bioscience, Faculty of Science, Medicine and Health , University of Wollongong , Wollongong , New South Wales 2522 , Australia.

Anal Chem ; 92(2): 1702-1711, 2020 01 21.

Article em En | MEDLINE | ID: mdl-31854977

Assuntos

Ampicilina/metabolismo; Superóxido Dismutase-1/metabolismo; Ampicilina/química; Dimerização; Humanos; Cinética; Espectrometria de Massas; Modelos Moleculares; Mutação Puntual; Desdobramento de Proteína; Proteínas Recombinantes/química; Proteínas Recombinantes/genética; Proteínas Recombinantes/metabolismo; Superóxido Dismutase-1/química; Superóxido Dismutase-1/genética; Termodinâmica

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Superóxido Dismutase-1 / Ampicilina Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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