Delaying Centrifugation and Freezing by Adding a Dihydropyrimidine Dehydrogenase Inhibitor Such as Gimeracil to Blood Sample Is Not a Valid Option to Simplify the Preanalytic Step for the Screening of Dihydropyrimidine Dehydrogenase Deficiency Using Uracilemia.

Launay, Manon; Nasser, Yara; Tholance, Yannick; Dellinger, Sandrine; Gonzalo, Philippe; Delavenne, Xavier

Launay, Manon; Nasser, Yara; Tholance, Yannick; Dellinger, Sandrine; Gonzalo, Philippe; Delavenne, Xavier.

Afiliação

Launay M; Department of Pharmacology, Toxicology and Blood Gases, University Hospital of Saint-Etienne, Saint-Etienne, France.
Nasser Y; Department of Pharmacology, Toxicology and Blood Gases, University Hospital of Saint-Etienne, Saint-Etienne, France.
Tholance Y; Department of Biochemistry, University Hospital of Saint-Etienne, Saint-Etienne, France.
Dellinger S; Department of Biochemistry, University Hospital of Saint-Etienne, Saint-Etienne, France.
Gonzalo P; CNRS UMR 5310, INSERM U1217, Synaptopathies and Autoantibodies, Institut NeuroMyoGene, University of Lyon, University Jean-Monnet, Saint-Étienne, France.
Delavenne X; Department of Pharmacology, Toxicology and Blood Gases, University Hospital of Saint-Etienne, Saint-Etienne, France.

Ther Drug Monit ; 42(2): 344-345, 2020 04.

Article em En | MEDLINE | ID: mdl-31855974

Assuntos

Centrifugação/métodos; Deficiência da Di-Hidropirimidina Desidrogenase/diagnóstico; Congelamento; Manejo de Espécimes/métodos; Di-Hidrouracila Desidrogenase (NADP)/antagonistas & inibidores; Humanos; Piridinas/administração & dosagem; Uracila/sangue

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Manejo de Espécimes / Centrifugação / Deficiência da Di-Hidropirimidina Desidrogenase / Congelamento Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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