Metabolomics study of the prefrontal cortex in a rat model of attention deficit hyperactivity disorder reveals the association between cholesterol metabolism disorder and hyperactive behavior.

Chen, Tianyi; Yuan, Haixia; Sun, Yu-Bo; Song, Yu-Chen; Lu, Manqi; Ni, Xinqiang; Han, Xinmin

Chen, Tianyi; Yuan, Haixia; Sun, Yu-Bo; Song, Yu-Chen; Lu, Manqi; Ni, Xinqiang; Han, Xinmin.

Afiliação

Chen T; First Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing, 210023, Jiangsu Province, China; Jiangsu Key Laboratory of Pediatric Respiratory Disease, Institute of Pediatrics, Nanjing University of Chinese Medicine, Nanjing, 210023, China; Medical Metabolomics Center, Nanjing Uni
Yuan H; First Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing, 210023, Jiangsu Province, China; Jiangsu Key Laboratory of Pediatric Respiratory Disease, Institute of Pediatrics, Nanjing University of Chinese Medicine, Nanjing, 210023, China; Medical Metabolomics Center, Nanjing Uni
Sun YB; School of Basic Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China. Electronic address: 20183013@njucm.edu.cn.
Song YC; First Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing, 210023, Jiangsu Province, China; Jiangsu Key Laboratory of Pediatric Respiratory Disease, Institute of Pediatrics, Nanjing University of Chinese Medicine, Nanjing, 210023, China. Electronic address: songyuchen071021@163
Lu M; First Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing, 210023, Jiangsu Province, China; Jiangsu Key Laboratory of Pediatric Respiratory Disease, Institute of Pediatrics, Nanjing University of Chinese Medicine, Nanjing, 210023, China. Electronic address: 18852086075@163.com.
Ni X; Pediatrics of Traditional Chinese Medicine, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen, 518038, Guangdong Province, China. Electronic address: nxq2bio@hotmail.com.
Han X; First Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing, 210023, Jiangsu Province, China. Electronic address: hxm1nj@163.com.

Biochem Biophys Res Commun ; 523(2): 315-321, 2020 03 05.

Article em En | MEDLINE | ID: mdl-31864712

Assuntos

Transtorno do Deficit de Atenção com Hiperatividade/metabolismo; Transtorno do Deficit de Atenção com Hiperatividade/psicologia; Colesterol/metabolismo; Córtex Pré-Frontal/metabolismo; Animais; Transtorno do Deficit de Atenção com Hiperatividade/tratamento farmacológico; Comportamento Animal/efeitos dos fármacos; Biomarcadores/metabolismo; Estimulantes do Sistema Nervoso Central/uso terapêutico; Modelos Animais de Doenças; Masculino; Redes e Vias Metabólicas; Metabolômica; Metilfenidato/uso terapêutico; Ratos; Ratos Endogâmicos SHR; Ratos Endogâmicos WKY

Palavras-chave

Attention deficit hyperactivity disorder; Cholesterol metabolism; Metabolomics; Methylphenidate; Prefrontal cortex; Spontaneous hypertensive rats

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtorno do Deficit de Atenção com Hiperatividade / Colesterol / Córtex Pré-Frontal Tipo de estudo: Risk_factors_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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