Efficacy of fractional carbon dioxide laser therapy for burn scars: a meta-analysis.
J Dermatolog Treat
; 32(7): 845-850, 2021 Nov.
Article
em En
| MEDLINE
| ID: mdl-31865824
ABSTRACT
BACKGROUND:
The present study evaluates the effectiveness of fractional carbon dioxide (CO2) laser for the treatment of burn scars.METHOD:
Literature search was conducted in electronic databases and studies were selected by following pre-determined eligibility criteria. Random effect meta-analyses were performed to achieve the effect size of the changes (mean difference (MD) between post-treatment and pretreatment values) in selected scar assessment scale scores and other important outcome measures.RESULTS:
14 studies were included. Treatment of burn scars with fractional CO2 laser significantly improved Vancouver Scar Scale (MD -3.01 [95% confidence interval (CI) -3.79, -2.22]; p Ë .00001), Patient and Observer Scar Assessment Scale (POSAS)- Patient (MD -14.38 [95% CI -17.62, -11.13]; p Ë .00001, POSAS - Observer (MD -8.81 [9% CI -11.60, -6.02]; p Ë .00001 and Scar Assessment Scale (MD 1.64 [95% CI 0.49, 2.78]; p = .005) scores especially with regards to pigmentation, vascularity, pliability, and height of scar. Pain and pruritis also improved with this treatment. Scar thickness measured with ultrasonography decreased non-significantly (MD -0.48 [95% CI -1.04, 0.09]; p = .1) whereas cutometer measures, R0 (scar firmness) and R2 (scar elasticity) did not change meaningfully.CONCLUSION:
Fractional CO2 laser therapy is a valuable tool for the treatment of burn scars which has potential for reducing scar severity.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Queimaduras
/
Cicatriz Hipertrófica
/
Terapia a Laser
/
Lasers de Gás
Tipo de estudo:
Etiology_studies
/
Systematic_reviews
Limite:
Humans
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article