BMP2 Modified by the m<sup>6</sup>A Demethylation Enzyme ALKBH5 in the Ossification of the Ligamentum Flavum Through the AKT Signaling Pathway.

Wang, Hai-Feng; Kuang, Ming-Jie; Han, Shi-Jie; Wang, An-Bang; Qiu, Jie; Wang, Feng; Tan, Bing-Yi; Wang, Da-Chuan

BMP2 Modified by the m⁶A Demethylation Enzyme ALKBH5 in the Ossification of the Ligamentum Flavum Through the AKT Signaling Pathway.

Wang, Hai-Feng; Kuang, Ming-Jie; Han, Shi-Jie; Wang, An-Bang; Qiu, Jie; Wang, Feng; Tan, Bing-Yi; Wang, Da-Chuan.

Afiliação

Wang HF; Department of Orthopedics, The Provincial Hospital Affiliated To Shandong University, Shandong, 250014, China.
Kuang MJ; Department of Orthopedics, The Provincial Hospital Affiliated To Shandong University, Shandong, 250014, China.
Han SJ; Department of Orthopedics, The Provincial Hospital Affiliated To Shandong University, Shandong, 250014, China.
Wang AB; Department of Orthopedics, The Provincial Hospital Affiliated To Shandong University, Shandong, 250014, China.
Qiu J; Department of Orthopedics, The Provincial Hospital Affiliated To Shandong University, Shandong, 250014, China.
Wang F; Department of Orthopedics, The Provincial Hospital Affiliated To Shandong University, Shandong, 250014, China.
Tan BY; Department of Orthopedics, The Provincial Hospital Affiliated To Shandong University, Shandong, 250014, China.
Wang DC; Department of Orthopedics, The Provincial Hospital Affiliated To Shandong University, Shandong, 250014, China. wangdachuansd@163.com.

Calcif Tissue Int ; 106(5): 486-493, 2020 05.

Article em En | MEDLINE | ID: mdl-31897529

Assuntos

Homólogo AlkB 5 da RNA Desmetilase; Proteína Morfogenética Óssea 2; Ligamento Amarelo; Ossificação Heterotópica; Proteínas Proto-Oncogênicas c-akt; Homólogo AlkB 5 da RNA Desmetilase/metabolismo; Proteína Morfogenética Óssea 2/metabolismo; Células Cultivadas; Desmetilação; Humanos; Ligamento Amarelo/metabolismo; Ligamento Amarelo/patologia; Ossificação Heterotópica/metabolismo; Osteogênese; Proteínas Proto-Oncogênicas c-akt/metabolismo; Transdução de Sinais; Vértebras Torácicas

Palavras-chave

ALKBH5; BMP2; OLF; m6A

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ossificação Heterotópica / Ligamento Amarelo / Proteínas Proto-Oncogênicas c-akt / Proteína Morfogenética Óssea 2 / Homólogo AlkB 5 da RNA Desmetilase Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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