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Photodegradation of (E)- and (Z)-Endoxifen in water by ultraviolet light: Efficiency, kinetics, by-products, and toxicity assessment.
Martin, Marina Ariño; Sivaguru, Jayaraman; McEvoy, John; Sonthiphand, Prinpida; Delorme, Andre; Khan, Eakalak.
Afiliação
  • Martin MA; Environmental and Conservation Sciences Program, North Dakota State University, Fargo, ND, 58108, USA; International Postgraduate Programs in Environmental Management, Graduate School, Chulalongkorn University, Bangkok, 10330, Thailand. Electronic address: marina_arino_martin@hotmail.com.
  • Sivaguru J; Center for Photochemical Sciences and Department of Chemistry, Bowling Green State University, Bowling Green, OH, 43403, USA. Electronic address: sivagj@bgsu.edu.
  • McEvoy J; Department of Microbiological Sciences, North Dakota State University, Fargo, ND, 58108, USA. Electronic address: john.mcevoy@ndsu.edud.
  • Sonthiphand P; Department of Biology, Mahidol University, Bangkok, 10400, Thailand. Electronic address: kwang_psp@hotmail.com.
  • Delorme A; Department of Science, Valley City State University, Valley City, ND, 58072, USA. Electronic address: andre.delorme@vcsu.edu.
  • Khan E; Department of Civil and Environmental Engineering and Construction, University of Nevada, Las Vegas, Las Vegas, NV, 89154, USA. Electronic address: eakalak.khan@unlv.edug.
Water Res ; 171: 115451, 2020 Mar 15.
Article em En | MEDLINE | ID: mdl-31901682
Endoxifen is an effective metabolite of a common chemotherapy agent, tamoxifen. Endoxifen, which is toxic to aquatic animals, has been detected in wastewater treatment plant (WWTP) effluent. This research investigates ultraviolet (UV) radiation (253.7 nm) application to degrade (E)- and (Z)-endoxifen in water and wastewater and phototransformation by-products (PBPs) and their toxicity. The effects of light intensity, pH and initial concentrations of (E)- and (Z)-endoxifen on the photodegradation rate were examined. Endoxifen in water was eliminated ≥99.1% after 35 s of irradiation (light dose of 598.5 mJ cm-2). Light intensity and initial concentrations of (E)- and (Z)-endoxifen exhibited positive trends with the photodegradation rates while pH had no effect. Photodegradation of (E)- and (Z)-endoxifen in water resulted in three PBPs. Toxicity assessments through modeling of the identified PBPs suggest higher toxicity than the parent compounds. Photodegradation of (E)- and (Z)-endoxifen in wastewater at light doses used for disinfection in WWTPs (16, 30 and 97 mJ cm-2) resulted in reductions of (E)- and (Z)-endoxifen from 30 to 71%. Two of the three PBPs observed in the experiments with water were detected in the wastewater experiments. Therefore, toxic compounds are potentially generated at WWTPs by UV disinfection if (E)- and (Z)-endoxifen are present in treated wastewater.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Raios Ultravioleta / Poluentes Químicos da Água Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Raios Ultravioleta / Poluentes Químicos da Água Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article