Chemokine CCL2 contributes to BBB disruption via the p38 MAPK signaling pathway following acute intracerebral hemorrhage.

Guo, Fuyou; Xu, Dingkang; Lin, Yazhou; Wang, Guoqing; Wang, Fang; Gao, Qiang; Wei, Qingjie; Lei, Shixiong

Guo, Fuyou; Xu, Dingkang; Lin, Yazhou; Wang, Guoqing; Wang, Fang; Gao, Qiang; Wei, Qingjie; Lei, Shixiong.

Afiliação

Guo F; Department of Neurosurgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, PR China.
Xu D; Department of Neurosurgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, PR China.
Lin Y; Department of Human Anatomy, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, PR China.
Wang G; Department of Neurosurgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, PR China.
Wang F; Department of Neurosurgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, PR China.
Gao Q; Department of Neurosurgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, PR China.
Wei Q; Department of Neurosurgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, PR China.
Lei S; Department of Neurosurgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, PR China.

FASEB J ; 34(1): 1872-1884, 2020 01.

Article em En | MEDLINE | ID: mdl-31914700

Assuntos

Barreira Hematoencefálica/metabolismo; Hemorragia Cerebral/metabolismo; Quimiocina CCL2/metabolismo; Transdução de Sinais/fisiologia; Proteínas Quinases p38 Ativadas por Mitógeno/metabolismo; Adulto; Idoso; Animais; Transporte Biológico/fisiologia; Encéfalo/metabolismo; Edema Encefálico/metabolismo; Modelos Animais de Doenças; Feminino; Humanos; Sistema de Sinalização das MAP Quinases/fisiologia; Masculino; Pessoa de Meia-Idade; Ratos; Ratos Sprague-Dawley; Acidente Vascular Cerebral/metabolismo

Palavras-chave

BBB; CCL2; PG; acute intracerebral hemorrhage; p38 MAPK

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Barreira Hematoencefálica / Transdução de Sinais / Hemorragia Cerebral / Quimiocina CCL2 / Proteínas Quinases p38 Ativadas por Mitógeno Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google