Advanced glycation end products induce immature angiogenesis in in vivo and ex vivo mouse models.

Chen, Lixian; Cui, Yun; Li, Bingyu; Weng, Jie; Wang, Weiju; Zhang, Shuangshuang; Huang, Xuliang; Guo, Xiaohua; Huang, Qiaobing

Chen, Lixian; Cui, Yun; Li, Bingyu; Weng, Jie; Wang, Weiju; Zhang, Shuangshuang; Huang, Xuliang; Guo, Xiaohua; Huang, Qiaobing.

Afiliação

Chen L; Department of Pathophysiology, Guangdong Provincial Key Laboratory of Shock and Microcirculation, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Cui Y; Department of Pathophysiology, Guangdong Provincial Key Laboratory of Shock and Microcirculation, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Li B; Department of Pathophysiology, Guangdong Provincial Key Laboratory of Shock and Microcirculation, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Weng J; Department of Pathophysiology, Guangdong Provincial Key Laboratory of Shock and Microcirculation, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Wang W; Department of Pathophysiology, Guangdong Provincial Key Laboratory of Shock and Microcirculation, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Zhang S; Department of Pathophysiology, Guangdong Provincial Key Laboratory of Shock and Microcirculation, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Huang X; Department of Pathophysiology, Guangdong Provincial Key Laboratory of Shock and Microcirculation, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Guo X; Department of Pathophysiology, Guangdong Provincial Key Laboratory of Shock and Microcirculation, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Huang Q; Department of Pathophysiology, Guangdong Provincial Key Laboratory of Shock and Microcirculation, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.

Am J Physiol Heart Circ Physiol ; 318(3): H519-H533, 2020 03 01.

Article em En | MEDLINE | ID: mdl-31922896

Assuntos

Produtos Finais de Glicação Avançada/farmacologia; Neovascularização Patológica/metabolismo; Retina/efeitos dos fármacos; Neovascularização Retiniana/metabolismo; Amidas/farmacologia; Animais; Aorta/efeitos dos fármacos; Aorta/metabolismo; Permeabilidade Capilar/efeitos dos fármacos; Camundongos; Camundongos Knockout; Proteínas dos Microfilamentos/metabolismo; Fosforilação/efeitos dos fármacos; Piridinas/farmacologia; Receptor para Produtos Finais de Glicação Avançada/genética; Receptor para Produtos Finais de Glicação Avançada/metabolismo; Retina/metabolismo; Transdução de Sinais/efeitos dos fármacos

Palavras-chave

RAGE; RhoA/ROCK; advanced glycation end products; moesin phosphorylation; pericyte

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Retina / Neovascularização Retiniana / Produtos Finais de Glicação Avançada / Neovascularização Patológica Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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