Substrate analogs that trap the 2'-phospho-ADP-ribosylated RNA intermediate of the Tpt1 (tRNA 2'-phosphotransferase) reaction pathway.

Dantuluri, Swathi; Abdullahu, Leonora; Munir, Annum; Katolik, Adam; Damha, Masad J; Shuman, Stewart

Dantuluri, Swathi; Abdullahu, Leonora; Munir, Annum; Katolik, Adam; Damha, Masad J; Shuman, Stewart.

Afiliação

Dantuluri S; Molecular Biology Program, Sloan-Kettering Institute, New York, New York 10065, USA.
Abdullahu L; Department of Chemistry, McGill University, Montreal, Quebec H3A0B8, Canada.
Munir A; Molecular Biology Program, Sloan-Kettering Institute, New York, New York 10065, USA.
Katolik A; Department of Chemistry, McGill University, Montreal, Quebec H3A0B8, Canada.
Damha MJ; Department of Chemistry, McGill University, Montreal, Quebec H3A0B8, Canada.
Shuman S; Molecular Biology Program, Sloan-Kettering Institute, New York, New York 10065, USA.

RNA ; 26(4): 373-381, 2020 04.

Article em En | MEDLINE | ID: mdl-31932322

Assuntos

Arabinose/análogos & derivados; Proteínas de Bactérias/metabolismo; Fosfotransferases (Aceptor do Grupo Álcool)/metabolismo; RNA/metabolismo; ADP-Ribosilação; Arabinose/metabolismo; Chaetomium/enzimologia; Clostridium thermocellum/enzimologia; Cytophagaceae/enzimologia; Proteínas Fúngicas/metabolismo; NAD/metabolismo; Fosfotransferases (Aceptor do Grupo Álcool)/química; RNA/química

Palavras-chave

ADP-ribosylation; RNA 2'-phosphotransferase; nicotinamide adenine dinucleotide; transesterification

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Arabinose / Proteínas de Bactérias / RNA / Fosfotransferases (Aceptor do Grupo Álcool) Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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