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Deciphering the enzymatic target of a new family of antischistosomal agents bearing a quinazoline scaffold using complementary computational tools.
Sebastian-Perez, Victor; García-Rubia, Alfonso; Seif El-Din, Sayed H; Sabra, Abdel-Nasser A; El-Lakkany, Naglaa M; William, Samia; Blundell, Tom L; Maes, Louis; Martinez, Ana; Campillo, Nuria E; Botros, Sanaa S; Gil, Carmen.
Afiliação
  • Sebastian-Perez V; Centro de Investigaciones Biológicas (CIB-CSIC), Madrid, Spain.
  • García-Rubia A; Centro de Investigaciones Biológicas (CIB-CSIC), Madrid, Spain.
  • Seif El-Din SH; Pharmacology Department, Theodor Bilharz Research Institute, Giza, Egypt.
  • Sabra AA; Pharmacology Department, Theodor Bilharz Research Institute, Giza, Egypt.
  • El-Lakkany NM; Pharmacology Department, Theodor Bilharz Research Institute, Giza, Egypt.
  • William S; Parasitology Department, Theodor Bilharz Research Institute, Giza, Egypt.
  • Blundell TL; Department of Biochemistry, University of Cambridge, Cambridge, UK.
  • Maes L; Laboratory for Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Antwerp, Belgium.
  • Martinez A; Centro de Investigaciones Biológicas (CIB-CSIC), Madrid, Spain.
  • Campillo NE; Centro de Investigaciones Biológicas (CIB-CSIC), Madrid, Spain.
  • Botros SS; Pharmacology Department, Theodor Bilharz Research Institute, Giza, Egypt.
  • Gil C; Centro de Investigaciones Biológicas (CIB-CSIC), Madrid, Spain.
J Enzyme Inhib Med Chem ; 35(1): 511-523, 2020 Dec.
Article em En | MEDLINE | ID: mdl-31939312
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinazolinas / Schistosoma mansoni / Aldeído Redutase / Inibidores Enzimáticos Tipo de estudo: Observational_studies / Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinazolinas / Schistosoma mansoni / Aldeído Redutase / Inibidores Enzimáticos Tipo de estudo: Observational_studies / Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article